Systemic lupus erythematosus Osteoporosis
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Signature of the Informed Consent Term; patients older than 40 years and female; followed up at HUPE; lupus diagnosed for at least 6 months (ACR criteria 1997, Hochberg, 1997); use of glucocorticoids for 3 years or more; patients with blood pressure (BP) equal to or greater than 100 x 70 mmHg
Exclusion criteria
Exclusion criteria: Presence of neurological / e or psychiatric disease that causes fear to the movements on the oscillating / vibratory platform; severe or incapacitating clinical illness; at the discretion of the investigator; Previous history of low-impact fracture and or classified as severe osteoporosis; personal history of avascular hip necrosis; active smoking; Alcoholism; use of joint protheses; patients refusing to sign the term Of Consent to participate in the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Increase in muscle activation at weeks 6 and 12 for WBV intervention obtained through surface electromyography (muscles - vastus lateralis, medial gastrocnemius and anterior tibialis of the lower right limb), with a variation of at least 5%.;Increase in handgrip strenght at weeks 6 and 12 for WBV intervention obtained through handgrip dynamometry, with a variation of at least 5% | — |
Secondary
| Measure | Time frame |
|---|---|
| Reductions in the measures of fatigue; at weeks 6 and 12 for WBV intervention using the FACIT-Fatigue scale of 13 items;with a variation of at least 5%.;Increase in the measures of fatigue; at weeks 6 and 12 for WBV intervention using the SF-36 questionnaire;with a variation of at least 5%.;Alterations in the measures of functionality; at weeks 6 and 12 for WBV intervention using the Health Assessment Questionnaire (HAQ) questionnaire in Portuguese;with a variation of at least 5%.;Reductions in the measures of falls risk; at weeks 6 and 12 for WBV intervention using the Timed Up and Go (TUG) test and the FES-I-Brazil questionnaire;with a variation of at least 5%. | — |
Countries
Brazil
Contacts
Universidade do Estado do Rio de Janeiro