Study conducted in humans, who present teeth with periodontal disease
Conditions
Interventions
Extraction of a tooth compromised by caries, fracture or periodontal disease. Two groups with a total of 20 participants, randomly divided, being a control group, with 10 individuals, performing the e
Procedure/surgery
D25.339.312
Sponsors
Universidade de Guarulhos
Universidade de Guarulhos
Eligibility
Age
20 Years to No maximum
Inclusion criteria
Inclusion criteria: Individuals who sought the specialization clinic in Implant Dentistry of the University of Guarulhos and had indication of previous exodontia to the installation of implants osseointegráveis, with more than 20 years; good general health, requiring extraction of a maximum of 2 contiguous teeth in the maxilla, the teeth being condemned for periodontal reasons, root fracture, caries and unsuccessful endodontic treatment.
Exclusion criteria
Exclusion criteria: Individuals under 20 years of age; smoking; people with diabetes; carriers of blood dyscrasias; patients who use anticoagulants; pregnant women; infants; patients who had dental elements with active infection.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To evaluate the effect of socket preservation after extraction using human recombinant bone morphogenetic protein type 2 (rhBMP2) to fill the human dental socket using computed tomography two days after extraction (T0) and after four months (T1 ). For the evaluation of the preservation of the sockets, using the tomographic images, the following dimensions were obtained: height of the buccal wall (Height V), determined in mm; height of the palatal wall (Height P), determined in mm and socket area, determined in mm2, obtained through the profile of the socket (edge), being delineated using the cursor and through a software tool. The data of height of the buccal wall, height of the palatine wall and area of the socket ridges, in the different periods of the study, and intergroup, within the same experimental period, were evaluated. In addition, the intragroup variation in the time intervals (T1 - T0), for the three variables studied, expressing the relation of reduction in height of the buccal and palatal bone wall and area.;Regarding height of the vestibular wall, the control group had an initial mean T0 of 7.64 mm + - 2.09 mm and after four months a mean T1 of 4.26 mm + - 1.68 mm demonstrating loss in height with significant statistical difference. The test group presented a mean initial height T0 of the buccal wall of 7.54 mm + - 4.16 mm and after four months T1 6.93 mm + - 4.06 mm, showing no statistically significant difference. When comparing both groups within the same time interval, no statistically significant difference of the initial means T0 was observed. However at the T1 moment, after four months, a statistically significant difference could be observed with a mean of 4.26mm + - 1.68mm and 6.93mm + - 4.06mm for the control and test groups respectively. Regarding the height of the palatine wall, the test group also had a superior behavior, since the test group did not present a statistically significant difference between the T0 and T1 times, while the con | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary outcomes are not expected. | — |
Countries
Brazil
Contacts
Public ContactWalterson Prado
Universidade de Guarulhos
Outcome results
None listed