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Paravertebral block to alleviate postoperative pain from robotic thoracic surgery: Comparison of the circulation changes caused by two different drugs used in the block, Dexamethasone and Dexmedetomidine

Paravertebral Block in postoperative analgesia for robotic thoracic surgeries: Comparison of hemodynamic changes caused by the adjuvants Dexamethasone and Dexmedetomidine

Status
Recruiting
Phases
Phase 2
Study type
Interventional
Source
REBEC
Registry ID
RBR-29fn5rq
Enrollment
Unknown
Registered
2025-10-09
Start date
2025-06-02
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Robotic Surgical Procedures

Interventions

This is a randomized, patient-blinded, cross-sectional study. A total of 42 individuals who meet the eligibility criteria will be probabilistically allocated to either of the intervention groups using

Sponsors

Universidade do Estado do Rio de Janeiro
Lead Sponsor
Gustavo Périssé Moreira Veras
Collaborator

Eligibility

Age
17 Years to No maximum

Inclusion criteria

Inclusion criteria: Age over 17 years; Classified as ASA 1 or 2; Classified as NYHA I or II; Thoracic surgeries by Robotics, in lateral position.

Exclusion criteria

Exclusion criteria: Pregnancy; Cognitive deficit and behavioral disorders; Use of stimulant or illegal drugs; Cardiopulmonary instability; Myocardial infarction or pulmonary embolism in the last 6 months; Cerebral, thoracic, or abdominal aneurysm; Previous thoracic surgery; Continuous home oxygen therapy; Autonomic disorders; Chronic use of alpha-adrenergic agonists; Inability to perform single-lung ventilation; Tumor in the trachea or vocal cords; Tracheal or bronchial stenosis; Use of anticoagulants; Chest wall infection.

Design outcomes

Primary

MeasureTime frame
It is expected that there will be no difference in the hemodynamic changes observed through minimally invasive hemodynamic monitoring in patients with paravertebral block performed with Ropivacaine and Dexamethasone compared to those with Ropivacaine and Dexmedetomidine, during robotic thoracic surgery, with a p-value less than 0.05, compared to data from the literature.

Secondary

MeasureTime frame
Evaluate the influence of capnothorax on hemodynamic behavior during robot-assisted surgeries, through minimally invasive hemodynamic measurements. ;Evaluate the effectiveness of postoperative analgesia of paravertebral block with dexamethasone and dexmedetomidine immediately after the patient wakes up at the end of robot-assisted thoracic surgery, through the Visual Pain Scale.

Countries

Brazil

Contacts

Public ContactGustavo Veras

Universidade do Estado do Rio de Janeiro

gustavoperisse@terra.com.br+55(21)999724016

Outcome results

None listed

Source: REBEC (via WHO ICTRP)