Urethra stenosis
Conditions
Interventions
This is a prospective randomized clinical study with blinded evaluation in randomized blocks. The sample will consist of 132 patients who will undergo anterior urethroplasty from June 2022 to June 202
Sponsors
Hospital de Clínicas de Porto Alegre
Hospital de Clínicas de Porto Alegre
Eligibility
Sex/Gender
Male
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Male; 18 years of age or older; diagnosis of urethral stenosis with indication of anterior urethroplasty
Exclusion criteria
Exclusion criteria: Posterior urethral stenosis; bladder neck sclerosis; vesicourethral anastomosis stricture; neurogenic etiology for urinary symptoms or requiring intermittent bladder catheterization; previous anterior urethroplasty; staged urethroplasty; urethral fistulas
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Surgical success in the groups with a duration of urethral catheterization (UCD) of 2 and 3 weeks verified by uroflowmetry, with a maximum flow equal to or greater than 15 ml/s after 12 months of treatment being considered successful. In patients with flow lower than 15 m/s, a urethral patency test with a 16 Fr urinary catheter or urethroscopy with a 17 Fr cystoscope will be performed. | — |
Secondary
| Measure | Time frame |
|---|---|
| Evaluate the rate of urinary infection and asymptomatic bacteriuria 4 weeks after the procedure with clinical examination and analysis of urine culture.;Check for changes in the International Prostate Symptom Score (IPSS) preoperatively, in the 3rd, 6th and 12th month after the procedure.;Check for changes in the Male Sexual Health Questionnaire for Ejaculatory Dysfunction (MSHQ-EJD), preoperatively, 3rd, 6th and 12th month after the procedure.;Check for changes in the International Index of Erectile Function (IIEF-5) score, preoperatively, in the 3rd, 6th and 12th month after the procedure.;Check for changes in the score of the questionnaire for patients undergoing urethral surgery (USS-PROM) in the preoperative period, in the 3rd, 6th and 12th month after the procedure. | — |
Countries
Brazil
Contacts
Public ContactPatric Tavares
Hospital de Clínicas de Porto Alegre
Outcome results
None listed