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Study to evaluate how the Yellow Fever vaccine works in individuals who have already taken the vaccine and undergone a stem cell transplant

Cross-sectional study of the immunogenicity evaluation of the Yellow Fever vaccine in individuals previously vaccinated after hematopoietic stem cell transplantation

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
REBEC
Registry ID
RBR-28h68rq
Enrollment
Unknown
Registered
2024-11-28
Start date
2023-10-15
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hematopoietic stem cell transplant

Interventions

This cross-sectional study will be conducted at the Special Immunobiological Reference Center (CRIE) of the Evandro Chagas National Institute of Infectious Diseases (INI/Fiocruz), in collaboration wit

Sponsors

Instituto Nacional de Infectologia - INI / Fiocruz
Lead Sponsor
Instituto Nacional de Infectologia - INI / Fiocruz
Collaborator

Eligibility

Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Individuals of both genders; aged 18 and older; post hematopoietic stem cell transplant at any time post-transplant and having received yellow fever vaccination pre-transplant; ability to comprehend and sign the informed consent form freely and with understanding

Exclusion criteria

Exclusion criteria: Vaccination against yellow fever after stem cell transplant; not having received yellow fever vaccination before the transplant; any condition that, in the Investigator's or their designees' assessment, may hinder the provision of informed consent, make participation in the study unsafe, impair data interpretation; or in any way interfere with the achievement of the study's objectives

Design outcomes

Primary

MeasureTime frame
It is expected that the Immune response to yellow fever vaccination in individuals undergoing hematopoietic stem cell transplantation (TCTH) will be present

Secondary

MeasureTime frame
No secondary outcomes are expected.

Countries

Brazil

Contacts

Public ContactLuciana Pedro

Instituto Nacional de Infectologia - INI / Fiocruz

luciana.pedro@ini.fiocruz.br+55(21)3865 9125

Outcome results

None listed

Source: REBEC (via WHO ICTRP)