Disorders resulting from impaired renal tubular function
Conditions
Interventions
In the day before the surgical procedure, the plasma creatinine value will be checked and the glomerular filtration rate calculated. Patients will remain fasted for at least eight hours for solid food
Other
Sponsors
Hospital São José
Unesp - Universidade Estadua Paulista Júlio de Mesquita Filho - Campus Botucatu
Eligibility
Age
20 Years to 80 Years
Inclusion criteria
Inclusion criteria: Age between 20 and 80 years; both sexes; physical status ASA II and III; preoperative creatinine values are less than 1.3 mg.dL-1.
Exclusion criteria
Exclusion criteria: Patients in emergency or urgent surgery; use of intra-aortic balloon counterpulsation in the preoperative period; left ventricular ejection fraction of less than 0.4; type III diastolic dysfunction.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of acute postoperative renal injury assessed within the first five days and two weeks after surgery according to the criteria proposed by the Acute Kidney Injury Network (AKIN), based on the creatinine values in plasma. For this purpose, plasma creatinine will be assessed within five days after surgery and two weeks after the surgical procedure, being an increase in serum creatinine greater than 1.5 times or an increase of more than 0.3 mg.dL when compared to the preoperative value, as well as a urine output lower than 0.5 mL.kg.h in 6 hours. | — |
Secondary
| Measure | Time frame |
|---|---|
| Incidence of chronic renal failure requiring renal replacement therapy at 30 and 90 days, as well as mortality at 30 and 90 days, will be considered. The need for renal replacement therapy considering the following indications: serum urea greater than 150 mg.dL with uremic symptoms; urine output less than 100 ml every twelve hours refractory to diuretics; serum potassium greater than 5.5 mmol.L refractory to medical treatment; pH less than 7.2 and serum bicarbonate less than 16 mEq.L in the arterial blood gas. | — |
Countries
Brazil
Contacts
Public ContactEric Lineburger
Hospital São José
Outcome results
None listed