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Haemodynamic effects of manual hyperinflation associated to PEEP in patients with septic shock

Haemodynamic effects of manual hyperinflation associated to PEEP in patients with septic shock

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
REBEC
Registry ID
RBR-283zts
Enrollment
Unknown
Registered
2015-08-13
Start date
2011-01-10
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

bacterial and fungal infections

Interventions

Control/placebo group (13 patients) will hold conventional respiratory physiotherapy with manual chest maneuvers for at least 10 minutes in the supine position. The analysis will be based on the effec
mean blood pressure in the pulmonary artery
pulmonary vascular resistance index
ejection fraction
arterial oxygen saturation
Rate consumption and oxygen extraction (VO2 and ERO2). The variables of 1 service will be evaluated in three distinct periods (before, immediately after and 30 minutes after the intervention). In both
Other
E02.779
H02.010.625

Sponsors

Hospital São Lucas da Pontificia Universidade Catolica do Rio Grande Do Sul
Lead Sponsor
Hospital São Lucas da Pontificia Universidade Catolica do Rio Grande Do Sul
Collaborator

Eligibility

Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 32 adult patients were included with septic shock who require the deployment catheter pulmonary artery; which signed the informed consent form and do not present any exclusion criteria.

Exclusion criteria

Exclusion criteria: Patients under the age of 18 years or over 80 years; pregnancy; acute myocardial infarction 3 months before the study; septic shock secondary to pulmonary disease; severe heart disease; with fractions of less than 30% ejection; and expectancy of less than 24 hours life.

Design outcomes

Primary

MeasureTime frame
Whether it was hoped that the practice of physical therapy, mean arterial pressure, mean pulmonary artery pressure, cardiac index and heart rate did not change in order to increase the hemodynamic instability of the patient, regardless of the evaluation period (before, right after the procedure, and 30 minutes after). Variables collected via catheter pulmonary artery and electronic monitor at the bedside.;In fact, regardless of physical therapy technique used, there were no hemodynamic changes in the collected variables (heart rate, mean arterial pressure, mean arterial pulmonary artery pressure, pulmonary vascular resistance index, cardiac index, ejection fraction)

Secondary

MeasureTime frame
It was expected improvement in oxygenation parameters following both types of respiratory therapy, through the analysis variables: arterial oxygen saturation; venous oxygen saturation; Rate consumption and oxygen extraction (VO2 and ERO2) assessed before, immediately after and 30 minutes after respiratory therapy. Variables collected via catheter pulmonary artery and electronic monitor at the bedside.;The data of arterial and venous oxygen saturation demonstrated significant increase independent of the technique used and evaluated during the time factor (after and 30 minutes after the procedure). The oxygen consumption rate (VO2) increased significantly after the procedure. Collected variables and calculated via a pulmonary artery catheter and electronic monitor at the bedside.

Countries

Brazil

Contacts

Public ContactClarissa;Clarissa Blattner Blattner;Blattner

Hospital São Lucas da Pontificia Universidade Catolica do Rio Grande Do Sul;Hospital São Lucas da PUCRS

clarissa.blattner@pucrs.br;cblattner@terra.com.br55(51)98243924;51-33203000

Outcome results

None listed

Source: REBEC (via WHO ICTRP)