Post-Acute COVID-19 Syndrome
Conditions
Interventions
This is a quasi-experimental, longitudinal, non-randomized, parallel-group clinical study involving 80 older adults of both sexes, allocated into three groups according to their history of SARS-CoV-2
the COVID-19 with persistent symptoms group (n = 27), composed of older adults with a previous confirmed diagnosis of COVID-19 and persistent symptoms consistent with post-COVID-19 condition
and the Control group (n = 26), composed of older adults with no history of COVID-19. Allocation will be based on clinical criteria, and a single-blind design will be adopted, with outcome assessors b
Sponsors
Universidade Unicesumar
Laboratório Interdisciplinar de Intervenção em Promoção da Saúde (LIIPS)
Eligibility
Age
60 Years to 79 Years
Inclusion criteria
Inclusion criteria: Older adults of both sexes, aged 60 to 79 years, with a self-reported history of COVID-19, with or without persistent symptoms, as well as older adults with no self-reported history of COVID-19, will be eligible for inclusion. All participants must be physically able to perform moderate- to vigorous-intensity exercise and be available to participate regularly in the study activities
Exclusion criteria
Exclusion criteria: Participants with debilitating neurological diseases such as Alzheimer’s disease; Parkinson’s disease, or plegias; or those with reduced intellectual capacity; will not be eligible for this study. Individuals currently using corticosteroids or with chronic or acute conditions that contraindicate physical exercise or may alter the response to the intervention will be excluded. Participants with disabling atherosclerotic disease, class 4 congestive heart failure, active rheumatoid arthritis, advanced renal or hepatic disease, undergoing chemotherapy for cancer, or other similar conditions will also be excluded. Finally, participants who attend less than 85% of the intervention sessions will not be considered
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To evaluate the improvement in persistent COVID-19 symptoms, physical fitness, nutritional profile, and mental health in older adults following a multidisciplinary intervention | — |
Secondary
| Measure | Time frame |
|---|---|
| Improvements are expected in the laboratory tests conducted one week before and after the intervention | — |
Countries
BR
Contacts
Public ContactAnderson Dos Santos
Universidade Unicesumar
Outcome results
None listed