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How using a positive pressure device affects Blood Pressure tiredness and quality of life in people with Sleep Apnea

Impact of Desaturation Index during Positive Pressure Device Therapy on blood pressure, excessive daytime impairment and quality of life in patients with Obstructive Sleep Apnea

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
REBEC
Registry ID
RBR-27dmxjc
Enrollment
Unknown
Registered
2025-07-31
Start date
2022-08-01
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Disorders of Excessive Somnolence

Interventions

This is a prospective observational study in which the participants are patients with severe obstructive sleep apnea (OSAS) with an apnea-hypopnea index (AHI) greater than 30, treated at the researche
V03.175.500

Sponsors

Departamento de Oftalmologia e Otorrinolaringologia do Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo
Lead Sponsor
Hospital Paranaense de Otorrinolaringologia
Collaborator

Eligibility

Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Patients of both sexes; aged 18 years or older; diagnosed with systemic arterial hypertension (SAH) for at least 6 months; with severe obstructive sleep apnea syndrome (OSAS); with a baseline apnea-hypopnea index (AHI) greater than 30 events per hour; with indication to start therapy with continuous positive airway pressure (CPAP) at Hospital IPO after clinical evaluation in the researcher's medical office. Last patient to be recruited on October 1, 2025

Exclusion criteria

Exclusion criteria: Patients younger than 18 years of age; baseline examination showing predominantly central sleep apnea; history of drug or alcohol abuse; presence of comorbidities such as congestive heart failure (CHF), chronic obstructive pulmonary disease (COPD), cerebrovascular disease or neuromuscular disorders; current smoking or smoking cessation less than 10 years ago; use of opioids or benzodiazepines; refusal to participate in any stage of the study; night work or shift work; previous use of any specific therapy for obstructive sleep apnea syndrome (OSAS) between the baseline polysomnography and the initial consultation with the researcher, including the use of continuous positive airway pressure (CPAP)

Design outcomes

Primary

MeasureTime frame
To evaluate, during the treatment of severe obstructive sleep apnea syndrome (OSAS) with continuous positive airway pressure (CPAP) in patients with systemic arterial hypertension (SAH), which parameter presents the best correlation with the clinical response in blood pressure (BP).—

Secondary

MeasureTime frame
On excessive daytime sleepiness (EDS) and quality of life—

Countries

Brazil

Contacts

Public ContactCintia Rosa

Hospital Paranaense de Otorrinolaringologia

nep@ipo.com.br+554130945648

Outcome results

None listed

Source: REBEC (via WHO ICTRP)