Lack or loss of sexual desire
Conditions
Interventions
Experimental group: 35 women with hypoactive sexual desire will receive transdermal biolipid-associated testosterone nanoemulsion (1 gram puff containing 300mcg / day). Control group: 35 women with hy
Drug
Sponsors
Universidade Federal de São Paulo - UNIFESP
Universidade Federal de São Paulo - UNIFESP
Eligibility
Sex/Gender
Female
Age
18 Years to 45 Years
Inclusion criteria
Inclusion criteria: Women between 18 and 45 years old with regular menstrual cycles; decreased sexual desire; sexual activity present with at least one sexual event per month with actual partner; be in good general health; use of an effective contraceptive method; women over 40 years old should have a clinically acceptable mammogram in the last 2 years;
Exclusion criteria
Exclusion criteria: Sexual dysfunction caused by another medical condition; body mass index (BMI) below 18 kg / m2 or above 35 kg / m2; undiagnosed genital bleeding; androgen therapy in the last 6 months; antiandrogen therapy for acne or hirsutism in the last 5 years; moderate or severe acne, hirsutism, or androgenetic alopecia; participant with any hyperandrogenic syndrome; any clinical illness or severe depression, active cancer, or treatment of malignancy in the last six months; pregnancy or breastfeeding; do not come to our center for follow-up study visits;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Evaluate behavioral changes with a tendency towards aggressiveness after the intervention, determined by a change of classification in a validated questionnaire (aggressiveness tendency assessment scale) applied at the beginning and end of the study | — |
Secondary
| Measure | Time frame |
|---|---|
| To determine improvement in sexual desire after intervention, assessed by increasing of the total score of a validated questionnaire (female sexual function index) applied at the beginning and end of the study | — |
Countries
Brazil
Contacts
Public ContactMaria Eugenia Lopes Cardoso
Universidade Federal de São Paulo - UNIFESP
Outcome results
None listed