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In-office Bleaching with low vs. high concentrate: a randomized clinical Ttrial

In-office Bleaching with low vs. high concentrate Hydrogen Peroxide: a randomized clinical trial

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
REBEC
Registry ID
RBR-275z28y
Enrollment
Unknown
Registered
2025-02-13
Start date
2024-10-25
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Tooth Discoloration

Interventions

The study was design as an equivalent, parallel, double-blinded randomized controlled trial and aims to compare the bleaching efficacy, as well as the risk and intensity of dental sensitivity after in
after that, they will be subjected to appropriate tests at a significance level of 5.
E06.420.750

Sponsors

Universidade Estadual de Ponta Grossa
Lead Sponsor
Universidade Estadual de Ponta Grossa
Collaborator

Eligibility

Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Volunteers aged at least 18 years, with good general and oral health, teeth free of carious lesions, gingival recessions or periodontal disease in the anterior region, who agree to the informed consent form (ICF) and who have at least one of their canines in A2 color or darker, according to the Vita Classical scale (Vita Zahnfabrik, Bad Säckingen, Germany) will be included in the study.

Exclusion criteria

Exclusion criteria: Volunteers who have previously undergone a whitening procedure, who report previous tooth sensitivity, who have dentures, fixed orthodontic appliances, restorations on the front teeth, endodontic treatment on the front teeth, teeth stained by tetracycline or fluorosis or who have visible cracks will be excluded from the study. In addition, patients who continuously use analgesic or anti-inflammatory medications, pregnant or lactating patients, and those with bruxism habits will be excluded.

Design outcomes

Primary

MeasureTime frame
To evaluate the bleaching efficacy after dental bleaching with different concentrations of hydrogen peroxide, using the Vita Classical and Vita Bleachedguide scales (?UEV) and the VitaEasyshade spectrophotometer (?Eab, ?E00 and WID);

Secondary

MeasureTime frame
To evaluate the absolute risk as well as the intensity of tooth sensitivity, using the Visual Analog Scale (VAS) 0-10 after the in-office bleaching procedure with hydrogen peroxide 6 vs. 35%.

Countries

Brazil

Contacts

Public ContactAlessandro Loguercio

Universidade Estadual de Ponta Grossa

aloguercio@hotmail.com+55 (42) 3220-3740

Outcome results

None listed

Source: REBEC (via WHO ICTRP)