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Evaluation of the benefit of different doses of dipyrone in third molar surgery

Evaluation of the efficacy of different doses of dipyrone in third molar surgery: clinical trial

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
REBEC
Registry ID
RBR-26frc3
Enrollment
Unknown
Registered
2019-10-10
Start date
2016-02-01
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Tooth not erupted

Interventions

Twenty six patients underwent biateral included lower third molars removal (52 surgeries). One side was the control (26 procedures), where dipyrone 500mg was used postoperatively. The opposite side wa
Drug

Sponsors

Universidade de Pernambuco
Lead Sponsor
Universidade de Pernambuco
Collaborator

Eligibility

Age
18 Years to 35 Years

Inclusion criteria

Inclusion criteria: Healthy patients aged between 18 and 35, thus patients who did not present systemic alterations nor used continuous medication. The lower third molars should have the same angulation (mesio-angular, rectangular, vertical or horizontal), similar root formation, and the same degree of impact as Pell and Gregory classification. The teeth should be impacted. The patient should also not have pericoronitis within the last 30 days before surgery, and the region could not have signs of inflammation.

Exclusion criteria

Exclusion criteria: Patients who did not agree to participate in the study after reading the consent form; had an allergy to the medicines used; did not fit the planning of surgical and anesthetic techniques; had a history of haematological disease or gastrointestinal bleeding; pregnant and lactating women; smokers; did not return to the second surgery (surgery on the opposite side); used other medications in the postoperative period; postoperative infection; difference greater than 10 minutes between the surgical times of the operated sides.

Design outcomes

Primary

MeasureTime frame
Expected Outcome 1 To Assessed the pain improvement with the use of dipyrone 1000mg through the visual analog scale, from the finding of a variation of at least 5% in the measurements

Secondary

MeasureTime frame
Expected Outcome 1 To assessed the improvement in patient satisfaction with 1000mg dipyrone use through the OHIP-14 questionnaire applied the week after surgery, from the finding of a variation of at least 5% in the measurements;Outcome found 2 The average of overall satisfaction, according to the OHIP-14 domains, also did not show significant differences.

Countries

Brazil

Contacts

Public ContactEmerson Nogueira

Universidade de Pernambuco

proec@upe.br+55 (81) 3183-3674

Outcome results

None listed

Source: REBEC (via WHO ICTRP)