Endoscopy Removal of Polyps from the Large Intestine and Rectum by the Water Immersion Technique

Colorectal Mucosectomy of Adenomas and Serrated Lesions by the Water Immersion Technique (Underwater): A Prospective Clinical Study

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

REBEC

Registry ID

RBR-262j28

Enrollment

Unknown

Registered

2020-08-17

Start date

2019-01-22

Completion date

Unknown

Last updated

2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Polyp of colon

Interventions

Underwater Endoscopic Mucosal Resection (UEMR): Colonoscopies were performed by two interventional endoscopists with experience in endoscopic mucosal resection (EMR), with more than 1000 EMRs perform

Fujifilm Corporation, Saitama-Shi, Saitama, Japan). CO2 insufflation was used for all procedures (GW-100

Fujifilm Corporation - Saitama-Shi, Saitama, Japan). Target-lesion macroscopic features were studied with 0.4% indigo-carmine chromoendoscopy and digital chromoendoscopy with Fuji Intelligent Color E

ERBE Elektromedizim, Tübingen, Germany). Paris and Kudo pit pattern endoscopic classifications were used to characterize the lesions. After lesion macroscopic assessment, the UEMR was started with eva

Procedure/surgery

E01.370.372.250.250.250

Eligibility

Inclusion criteria

Inclusion criteria: Patients with lesions without endoscopic stigmata of deep submucosal invasion, equal to or greater than 5 mm in length and considered suitable to endoscopic resection. Lesions not previously detected but which were identified during the study's procedure and fulfilled these criteria were also included.

Exclusion criteria

Exclusion criteria: Exclusion criteria were lesions that showed signs of malignant degeneration or deep submucosal invasion (depression, ulceration, friability, bleeding, induration, Kudo pit pattern V); pedunculated polyps; patients with familial polyposis syndromes; those with contraindications (e.g. coagulation disorders and other comorbidities) for endoscopic resection by any technique and patients who did not agree to participate in the research.

Design outcomes

Primary

Measure	Time frame
To evaluate the viability of underwater endoscopic mucous resection (UEMR) using descriptive statistics techniques such as measuring averages / medians, building graphs and tables of the resection failure due to technical difficulty.;To evaluate the effectiveness of underwater endoscopic mucous resection (UEMR) using descriptive statistics techniques such as measuring averages / medians, building graphs and tables of the complete resection rate and block resection rate;To evaluate the safety of underwater endoscopic mucous resection (UEMR) using descriptive statistical techniques such as measuring averages / medians, building graphs and tables of adverse events	—

Measure

Time frame

To evaluate the viability of underwater endoscopic mucous resection (UEMR) using descriptive statistics techniques such as measuring averages / medians, building graphs and tables of the resection failure due to technical difficulty.;To evaluate the effectiveness of underwater endoscopic mucous resection (UEMR) using descriptive statistics techniques such as measuring averages / medians, building graphs and tables of the complete resection rate and block resection rate;To evaluate the safety of underwater endoscopic mucous resection (UEMR) using descriptive statistical techniques such as measuring averages / medians, building graphs and tables of adverse events

—

Secondary

Measure	Time frame
To evaluate the resection time by timing the procedure from the beginning of the instillation of water in the intestinal lumen to the end of the resection	—

Countries

Brazil

Contacts

Public ContactPedro Nogueira

Hospital Madre Teresa

pedro1612@hotmail.com+553133398000

Outcome results

None listed

Source: REBEC (via WHO ICTRP)