Postoperative Nausea and Vomiting Postoperative Pain
Conditions
Interventions
Thirty participants will be randomly allocated into two groups in a randomized, double-blind clinical trial. Group 1 (n=15), Transversus Abdominis Plane Block group: participants will receive a bilate
Sponsors
Hospital Naval Marcílio Dias
Instituto de Pesquisas Biomédicas do Hospital Naval Marcílio Dias
Eligibility
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: Users of the Brazilian Navy Health System; both sexes; age between 18 and 70 years; American Society of Anesthesiologists physical status I or II; indication for elective Laparoscopic Cholecystectomy; provision of voluntary informed consent
Exclusion criteria
Exclusion criteria: Refusal to participate; age lower than 18 years or greater than 70 years; American Society of Anesthesiologists physical status greater than II; allergy to any study medication; Emergency Surgery; Chronic Pain; Acalculous Biliary Disease; pregnancy; class III obesity with body mass index greater than 35 kilograms per square meter
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Evaluate postoperative opioid consumption within the first 24 hours after surgery; verified by measuring the cumulative dose of rescue opioids administered during the postoperative period, expressed as morphine milligram equivalents; lower opioid consumption is expected in the transversus abdominis plane block group compared with the intravenous multimodal analgesia group | — |
Secondary
| Measure | Time frame |
|---|---|
| Evaluate postoperative pain intensity 15 minutes after admission to the post-anesthesia care unit; verified using the Visual Analog Scale for pain assessment; lower pain scores are expected in the transversus abdominis plane block group compared with the intravenous multimodal analgesia group;Evaluate postoperative pain intensity 60 minutes after admission to the post-anesthesia care unit; verified using the Visual Analog Scale for pain assessment; lower pain scores are expected in the transversus abdominis plane block group compared with the intravenous multimodal analgesia group;Evaluate postoperative pain intensity within the first 24 hours after surgery; verified using the Visual Analog Scale for pain assessment; lower pain scores are expected in the transversus abdominis plane block group compared with the intravenous multimodal analgesia group;Evaluate the incidence of Postoperative Nausea and Vomiting within the first 24 hours after surgery; verified through standardized clinical assessment and the need for rescue antiemetic medication; lower incidence of Postoperative Nausea and Vomiting is expected in the transversus abdominis plane block group compared with the intravenous multimodal analgesia group;Evaluate hospital length of stay after surgery; verified by measuring the time interval in hours between the end of surgery and hospital discharge; shorter hospital stay is expected in the transversus abdominis plane block group compared with the intravenous multimodal analgesia group;Evaluate patient satisfaction with postoperative analgesia within the first 24 hours after surgery; verified using a standardized satisfaction scale; higher satisfaction scores are expected in the transversus abdominis plane block group compared with the intravenous multimodal analgesia group | — |
Countries
BR
Contacts
Public ContactBruno Santiago
Hospital Naval Marcílio Dias
Outcome results
None listed