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Effect of the pH, consistency and quantity of fluoride of the toothpaste in the fluoride retention on enamel surface

Effect of the pH, consistency and fluoride concentration of liquid dentifrices in caries control of fluoridated and not fluoridated áreas: randomized clinical trials

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
REBEC
Registry ID
RBR-25b7xh
Enrollment
Unknown
Registered
2014-10-21
Start date
2013-08-02
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Dental Fluorosis

Interventions

Nineteen adults took part in the study. All the paticipants will take part in the three interventions after a washout period of one week between them. Interventional group 1 - will use a liquid denti
Interventional group 2 - will use a DLE with 1100 ppm F, pH 7.0, and high fluidity (1.1% CMC)
Active Control group - will use a commercial toothpaste with 1,100 ppm F, pH 7.0 and fluidity conventional (Sorriso Fresh ®).
Other

Sponsors

Faculdade de Odontologia de Bauru
Lead Sponsor
Coordenação de Aperfeiçoamento de Pessoal de Nível Superior
Collaborator

Eligibility

Age
20 Years to 35 Years

Inclusion criteria

Inclusion criteria: Healthy volunteers, aged between 20 and 35 years old, not using orthodontic appliances and that have not been involved in other studies 3 months before the present research.

Exclusion criteria

Exclusion criteria: Volunteers using orthodontic appliances; volunteers using other fluoridated products.

Design outcomes

Primary

MeasureTime frame
Significantly higher concentrations of fluoride in the biofilm fluid were found 1 hr after the toothbrushing compared to 12 h (p <0.01). However, no significant differences were seen between the dentifrices with different viscosities.

Secondary

MeasureTime frame
Significant differences between the dentifrice could be found if their viscosity was quite different. Higher concentrations of F in dentifrices can lead to significant differences if their viscosity was very different. Higher concentrations of F in the dentifrices can lead to different results regarding the effect on the incorporation of F in the biofilm according to the viscosity.

Countries

Brazil

Contacts

Public ContactCristiane Cardoso

Faculdade de Odontologia de Bauru

crisabc83@gmail.com+55 (14) 32358246

Outcome results

None listed

Source: REBEC (via WHO ICTRP)