Use of Dialkyl Carbamoyl Chloride (DACC) to aid in the healing of challenging wounds

Use of Dialkyl Carbamoyl Chloride (DACC) in the prevention and treatment of Hard-to-Heal Wounds

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

REBEC

Registry ID

RBR-24mkxp8

Enrollment

200

Registered

2026-02-04

Start date

2026-01-05

Completion date

Unknown

Last updated

2026-03-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Wound Healing

Interventions

This is a randomized controlled clinical trial with two arms. Intervention group: 100 patients in the postoperative period of cardiac surgery using a dressing coated with Dialkyl Carbamoyl Chloride (D

s group one day before surgery. Masking will not be possible, as the intervention dressing is green/blue in color. Follow-up will be performed at 48 hours, 7 days, 14 days, 30 days, or 90 days (in pro

Eligibility

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Postoperative cardiac surgery patients; both genders; over 18 years of age; who are not immunosuppressed; who do not abuse psychoactive substances

Exclusion criteria

Exclusion criteria: Known allergy or sensitivity to the components of the Dialkyl Carbamoyl Chloride (DACC) dressing

Design outcomes

Primary

Measure	Time frame
A lower incidence of sternal surgical site infection is expected in patients undergoing cardiac surgery who use dressings coated with dialkyl carbamoyl chloride compared to patients using conventional dressings with surgical site infection assessed based on clinical and diagnostic criteria adopted by the health service and data collected at 48 hours, 7 days, 14 days, 30 days and 90 days after surgery	—

Measure

Time frame

A lower incidence of sternal surgical site infection is expected in patients undergoing cardiac surgery who use dressings coated with dialkyl carbamoyl chloride compared to patients using conventional dressings with surgical site infection assessed based on clinical and diagnostic criteria adopted by the health service and data collected at 48 hours, 7 days, 14 days, 30 days and 90 days after surgery

—

Secondary

Measure	Time frame
A reduction in the occurrence of skin reactions irritation, detachment, maceration or the need for early dressing changes is expected in patients using dressings coated with dialkyl carbamoyl chloride	—

Countries

Brazil

Contacts

Public ContactMaria Carvalho

Universidade Estadual do Ceará

bnuunes15@gmail.com+55(85)99971-7046

Outcome results

None listed

Source: REBEC (via WHO ICTRP) · Data processed: Mar 14, 2026