Maintenance of bone support after tooth extraction with autologous dentin material.

Bone preservation of dental alveoli after extraction with autologous dentin Material

Status

Recruiting

Phases

Phase 1

Study type

Interventional

Source

REBEC

Registry ID

RBR-24mdgrf

Enrollment

Unknown

Registered

2021-08-11

Start date

2021-04-27

Completion date

Unknown

Last updated

2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

bone reabsorbtion

Interventions

A sample of 140 patients with biomaterial will be taken, of which: 40 will be regenerated with dentin, 40 with dentin and PRP and finally 20 will be taken as a control sample of the empty socket. Then

D001861

Eligibility

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Inclusion criteria: Patients over 18 years old; ASA I; who present vertically fractured teeth; penetrating cavities; coronary fracture; teeth with periodontal disease Stage III and IV degree B,C; alveoli are more than 3mm deep.

Exclusion criteria

Exclusion criteria: Exclusion criteria: Systemically compromised patients; minors; patients with any contraindication to surgery; patients who do not want to participate in the study.

Design outcomes

Primary

Measure	Time frame
Alveolar preservation is a method to reduce bone resorption after extraction and thus facilitate dental implant placement. The use of various regenerative materials is common to reduce collapse since the reduction of the alveolar ridge after average dental extraction occurs in 1.24 mm vertically and 3.74 mm horizontally in the first 6 months. After performing bone regeneration with autologous dentin material, it is expected that by measuring the housfield degrees, comparing the findings of the initial tomography and the second tomography performed at six months, the changes made in said processes in each study group comparing it with the control group, this would be done in April-June 2022	—

Measure

Time frame

Alveolar preservation is a method to reduce bone resorption after extraction and thus facilitate dental implant placement. The use of various regenerative materials is common to reduce collapse since the reduction of the alveolar ridge after average dental extraction occurs in 1.24 mm vertically and 3.74 mm horizontally in the first 6 months. After performing bone regeneration with autologous dentin material, it is expected that by measuring the housfield degrees, comparing the findings of the initial tomography and the second tomography performed at six months, the changes made in said processes in each study group comparing it with the control group, this would be done in April-June 2022

—

Secondary

Measure	Time frame
Alveolar preservation is a method to reduce bone resorption after extraction and thus facilitate dental implant placement. The use of various regenerative materials is common to reduce collapse since the reduction of the alveolar ridge after average dental extraction occurs in 1.24 mm vertically and 3.74 mm horizontally in the first 6 months. After performing bone regeneration with autologous dentin material, it is expected that through the performance of an analysis Histomorphometry allows the quantitative assessment of bone tissue by counting and measuring microstructural variables; In this way, information about bone turnover (remodeling), microarchitecture and dynamic and static cell activity can be obtained, this would be done in April-June 2022	—

Measure

Time frame

Alveolar preservation is a method to reduce bone resorption after extraction and thus facilitate dental implant placement. The use of various regenerative materials is common to reduce collapse since the reduction of the alveolar ridge after average dental extraction occurs in 1.24 mm vertically and 3.74 mm horizontally in the first 6 months. After performing bone regeneration with autologous dentin material, it is expected that through the performance of an analysis Histomorphometry allows the quantitative assessment of bone tissue by counting and measuring microstructural variables; In this way, information about bone turnover (remodeling), microarchitecture and dynamic and static cell activity can be obtained, this would be done in April-June 2022

—

Countries

Dominican Republic

Contacts

Public ContactLuís Espíndola-Castro

luis.espindola@upe.br(81)997867662

Outcome results

None listed

Source: REBEC (via WHO ICTRP) · Data processed: Feb 2, 2026