chronic periodontitis
Conditions
Interventions
Thirty-three individuals were randomly allocated, by lot, into three independent groups:
Group I: 11 individuals and 88 sites. SRP + 10% DOX Gel
Group II: 12 individuals and 96 sites. SRP + 10% DOX ge
Drug
Device
Procedure/surgery
Sponsors
Universidade Federal de Minas Gerais
Universidade Federal de Minas Gerais
Eligibility
Age
18 Years to 45 Years
Inclusion criteria
Inclusion criteria: Individuals presenting chronic periodontitis (AAP-1999); individuals with contralateral quadrants containing at least one molar with presence of sites with probing depth 5 mm, clinical insertion level 6 mm and bleeding at probing; over 18 years.
Exclusion criteria
Exclusion criteria: Presence of periapical and pulpal alterations; presence of gingivitis and acute periodontal conditions (abscesses and acute necrotizing periodontitis); presence of candidosis and changes in the mucosa; allergy to the components of gels and periodontal dressings; presence of systemic diseases (cardiovascular, blood dyscrasias, immunodeficiencies, transplanted, diabetes, osteoporosis, nephropathies, hepatopathies); need for antibiotic prophylaxis before periodontal treatment; use of systemic antibiotics, chemotherapeutics of controlled or continuous use and others that may interfere with the inflammatory process or have adverse effects directly in the periodontium in the last 6 months; pregnancy and contraceptive users during the study and during the previous three months or lactation; smokers; surgical or non-surgical periodontal treatment in the last 6 months; treatment with chlorhexidine mouthwash 0.12% or other topical chemical agent in the last 6 months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The parameter clinical attachment level (CAL greater than or equal to 6 mm) was selected as the main variable for the determination of periodontitis and also to determine the size of the sample N;Outcome found 1: Mean difference in gain of clinical attachment level. The level of significance was 5% (p <0.05) | — |
Secondary
| Measure | Time frame |
|---|---|
| Expected outcome 2: periodontal probing depth greater than or equal to 5mm, expected outcome 3: bleeding on probing, present or absent, expected outcome 4: visible plaque index, present or absent, expected outcome 5: interproximal radiographic density, using the fractal analysis technique before and after the treatments. The level of significance was 5% (p <0.05);Outcome found 2: mean difference in reduction of periodontal probing depth, outcome found 3: mean difference in reduction of bleeding on probing, outcome found 4: mean difference in reduction of visible plaque index, outcome found 5: mean difference in gain of interproximal radiographic density, using the fractal analysis technique before and after the treatments. The level of significance was 5% (p <0.05) | — |
Countries
Brazil
Contacts
Public ContactVivianne Trajano
Universidade Federal de Minas Gerais
Outcome results
None listed