Effect of arm anesthesia on vein size in patients undergoing fistula surgery for hemodialysis

Effect of brachial plexus anesthetic block on the diameter of superficial upper-limb veins in patients undergoing autologous arteriovenous fistula creation: a randomized clinical trial

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

REBEC

Registry ID

RBR-23qwk7y

Enrollment

Registered

2026-07-14

Start date

2026-07-09

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Renal Dialysis

Interventions

This is a two-arm open-label randomized controlled trial with a total of 80 participants allocated by simple randomization using computer-generated software with the allocation sequence generated in a

Eligibility

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Age 18 years or older; clinical indication for autologous arteriovenous fistula creation for hemodialysis, in radiocephalic, brachiocephalic or brachiobasilic configuration; agreement to participate with signed informed consent form

Exclusion criteria

Exclusion criteria: Known allergy to local anesthetics; active infection at the brachial plexus block puncture site; severe coagulopathy; preexisting upper limb neuropathy; inability to attend regular outpatient follow-up

Design outcomes

Primary

Measure	Time frame
To assess the diameter of the superficial vein cephalic or basilic according to the site planned for the anastomosis by Doppler ultrasound in the preoperative period after onset of the anesthetic block and before the surgical incision.	—

Secondary

Measure	Time frame
To assess the functional patency of the arteriovenous fistula at sixty days, as a hypothesis-generating secondary outcome, defined by the criteria of Beathard et al 2018: venous diameter greater than or equal to 6 mm, flow greater than or equal to 500 mL per minute, depth less than or equal to 6 mm from the skin, palpable thrill and absence of stenoses greater than 50 percent with results reported with 95 percent confidence interval.;To assess the preoperative arterial diameter after the anesthetic block by Doppler ultrasound.;To assess the blood flow in the brachial artery by Doppler ultrasound.;To assess perioperative complications: thrombosis, hematoma, infection, steal syndrome and bleeding that require reintervention or ligation of the fistula.	—

Measure

Time frame

To assess the functional patency of the arteriovenous fistula at sixty days, as a hypothesis-generating secondary outcome, defined by the criteria of Beathard et al 2018: venous diameter greater than or equal to 6 mm, flow greater than or equal to 500 mL per minute, depth less than or equal to 6 mm from the skin, palpable thrill and absence of stenoses greater than 50 percent with results reported with 95 percent confidence interval.;To assess the preoperative arterial diameter after the anesthetic block by Doppler ultrasound.;To assess the blood flow in the brachial artery by Doppler ultrasound.;To assess perioperative complications: thrombosis, hematoma, infection, steal syndrome and bleeding that require reintervention or ligation of the fistula.

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Countries

Contacts

Public ContactThiago Amorim

Hospital das Clínicas da Universidade Federal de Pernambuco

thiagoowa@gmail.com+55(82)993020589

Outcome results

None listed

Source: REBEC (via WHO ICTRP) · Data processed: Aug 10, 2026