Ventilator-associated pneumonia, artificial respiration, physical therapy modalities
Conditions
Interventions
The subjects included in the study (n=20) will be initially positioned in dorsal decubitus with head elevation at 30 degrees and will be submitted to endotracheal suction to clear pulmonary secretion.
• Five cycles with PEEP = 15 cmH2O, driving pressure = 15 cmH2O, on pressure control ventilation mode, and at the end of the inspiratory time of the fifth cycle, PEEP will be rapidly reduced to zero c
• Five cycles with PEEP = 15 cmH2O, tidal volume to achieve a driving pressure of 15 cmH2O, on volume control ventilation mode, and at the end of the inspiratory time of the fifth cycle, PEEP will be
Procedure/surgery
E02.779
Sponsors
Universidade Federal do Triângulo Mineiro
Universidade Federal do Triângulo Mineiro
Eligibility
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Patients with pulmonary secretion on mechanical invasive ventilation; hemodynamically stable (MBP higher than 65 mmHg); PEEP lower or equal than 10 cmH2O; oxygen inspiratory fraction lower or equal than 0,4; peripheral oxygen saturation higher than 90%.
Exclusion criteria
Exclusion criteria: Intracranial hypertension; cor pulmonale; pulmonary hypertension; pregnancy; pneumothorax not drained; rib fractures; thoracic drain tube.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Mean difference of expiratory flow bias (peak expiratory flow minus peak inspiratory flow) between PEEP-ZEEP maneuver applied in pressure control vs. volume control mode of at least 15 L/min.;Mean difference of expiratory flow bias (peak expiratory flow minus peak inspiratory flow) between PEEP-ZEEP maneuver applied with manual thoracic compression vs. without compression of at least 5 L/min. | — |
Secondary
| Measure | Time frame |
|---|---|
| Equivalence on hemodynamics and respiratory mechanic during the 30-minute-interval after PEEP-ZEEP performance in volume control vs. pressure control, and after PEEP-ZEEP with thoracic compression vs no compression. | — |
Countries
Brazil
Contacts
Public ContactMarcia Volpe
Universidade Federal do Triângulo Mineiro
Outcome results
None listed