Depression
Conditions
Interventions
This is a two-arm, double-blind, randomized controlled clinical trial. The intervention will last for six months. Each of the control and intervention groups will consist of 40 volunteers with the und
G11.427.410.698.277
Sponsors
Instituto Nacional de Infectologia Evandro Chagas - Fundação Oswaldo Cruz
Instituto Nacional de Infectologia Evandro Chagas - Fundação Oswaldo Cruz
Eligibility
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Serological positivity for Chagas disease; both sexes; absence of symptoms and or clinical signs of cardiac and / or digestive disorders associated with Chagas disease.
Exclusion criteria
Exclusion criteria: Age below 18 years; cardiopathies of non-chagasic etiology; osteomioarticular changes that make it impossible to perform the physical exercise protocol; clinical contraindication for physical exercise; regular physical exercise in the last 2 months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Evaluate the effect of a home based physical exercise program in patients with the chronic indeterminate form of Chagas disease in cardiorespiratory fitness that will be assessed using the cardiopulmonary stress test;Evaluate the effect of a home based physical exercise program in patients with the chronic indeterminate form of Chagas disease in flexibility, which will be assessed using the sit and reach test;Evaluate the effect of a home based physical exercise program on patients with chronic indeterminate form of Chagas disease in strength using manual dynamometry;Evaluate the effect of a home based physical exercise program on patients with the chronic indeterminate form of Chagas disease in Quality of Life, using the World Health Organization's abbreviated quality of life assessment instrument, validated for use in the population the WHOQOL-Bref;Evaluate the effect of a home based exercise program on patients with the chronic indeterminate form of Chagas disease in the symptoms of depression using the Beck Depression Inventory;Evaluate the effect of a home based physical exercise program on patients with the indeterminate chronic form of Chagas disease in anxiety symptoms using the Beck Anxiety Inventory;Evaluate the effect of a home based physical exercise program on patients with an undetermined chronic form of Chagas disease under stress, using the validated perception stress scale (PSS);Evaluate the effect of a home based physical exercise program on patients with an undetermined chronic form of Chagas disease on nutritional status through anthropometric measurements and body composition;Evaluate the effect of a home based physical exercise program on patients with an undetermined chronic form of Chagas disease on sleep quality, using the Pittsburgh Sleep Quality Index;Evaluate the effect of a home based physical exercise program on patients with an undetermined chronic form of Chagas disease on biomarkers of lipid, inflammatory and cardiac function profile | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary outcomes are not expected | — |
Countries
Brazil
Contacts
Public ContactMauro Felippe Mediano
Instituto Nacional de Infectologia Evandro Chagas - Fundação Oswaldo Cruz
Outcome results
None listed