Biofilms
Conditions
Interventions
This is a randomized controlled clinical trial with a crossover design, without masking of participants or researchers due to the use of 0.5% sodium hypochlorite as the control solution, a substance w
Sponsors
Universidade de Pernambuco
Universidade de Pernambuco
Eligibility
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Adult patients; both genders; bimaxillary completely edentulous; users of complete dentures fabricated with heat-polymerized acrylic resin; in good general and oral health; intact and healthy mucosa without signs or symptoms of denture stomatitis; use of well-fitting dentures; availability to attend the clinic during intervention and data collection periods
Exclusion criteria
Exclusion criteria: Participants with hypersensitivity to sodium hypochlorite; smokers; history of untreated xerostomia or hyposalivation; participants with dentures installed less than 3 months ago; participants with broken, fractured, or relined dentures; participants lacking cognitive capacity to understand and follow the experimental protocol or respond to the questionnaire
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| It is expected to evaluate the reduction of microbiological biofilm on complete dentures, verified through microbiological sampling and laboratory analysis, based on the quantification of microbial load before and after the interventions. | — |
Secondary
| Measure | Time frame |
|---|---|
| It is expected to evaluate the amount of visible biofilm in the upper complete dentures, verified by staining with a 1% neutral red solution, based on the measurement of the biofilm area after staining.;It is expected to evaluate the satisfaction of the participants, verified through the application of a structured questionnaire, based on the analysis of the quantitative and qualitative responses obtained. | — |
Countries
Brazil
Contacts
Public ContactSandra Moraes
Universidade de Pernambuco
Outcome results
None listed