Study to evaluate hydration in the prevention of blemishes after varicose vein treatment

Prospective study of the impact of skin hydration on the incidence of post-sclerotherapy hyperpigmentation

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

REBEC

Registry ID

RBR-10yk36ht

Enrollment

Unknown

Registered

2025-07-29

Start date

2024-02-10

Completion date

Unknown

Last updated

2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

varicose veins

Interventions

Prospective clinical trial, randomized 1:1, using Redcap software, blinded to the evaluators. Total number of study participants: 55. On day 0, patients answered a questionnaire about the quality of l

E02.319.805

Eligibility

Sex/Gender

Female

Age

18 Years to 40 Years

Inclusion criteria

Inclusion criteria: women. fitzpatrick III to IV. formal indication to sclerotherapy

Exclusion criteria

Exclusion criteria: Men. Patients < 18 years old. patients with any contraindication to the sclerotherapy procedure

Design outcomes

Primary

Measure	Time frame
Expected outcome 1: To evaluate the impact of skin hydration in preventing the appearance of hyperpigmentation after sclerotherapy with polidocanol;Outcome found 1: The effect of skin hydration in preventing hyperchromia after sclerotherapy was evaluated, a positive relationship was found, however, without statistical relevance.	—

Secondary

Measure	Time frame
Expected outcome 2: Skin hydration has a positive impact on the patient's perceived improvement in quality of life after sclerotherapy.;Outcome found 2: There was no perceived increase in quality of life in the group of women randomized to receive hydration. ;Expected outcome 3: Patients with higher Fitzpatrick scale are more prone to spots after sclerotherapy;Outcome found 3 : There was a higher incidence of spots in patients with a higher Fitzpatrick scale after sclerotherapy	—

Measure

Time frame

Expected outcome 2: Skin hydration has a positive impact on the patient's perceived improvement in quality of life after sclerotherapy.;Outcome found 2: There was no perceived increase in quality of life in the group of women randomized to receive hydration. ;Expected outcome 3: Patients with higher Fitzpatrick scale are more prone to spots after sclerotherapy;Outcome found 3 : There was a higher incidence of spots in patients with a higher Fitzpatrick scale after sclerotherapy

—

Countries

Brazil

Contacts

Public ContactMariana Rodrigues

Universidade Federal do Rio Grande

maripeugeot@gmail.com+55 (53)3237-3013

Outcome results

None listed

Source: REBEC (via WHO ICTRP)