Type 2 Diabetes
Conditions
Interventions
It's a double-blind, three-arm parallel, randomized clinical trial. Experimental group 1: 41 participants with periodontitis and type 2 diabetes mellitus will receive non-surgical periodontal treatmen
Sponsors
Universidade Guarulhos
Universidade Guarulhos
Eligibility
Age
30 Years to No maximum
Inclusion criteria
Inclusion criteria: Stages III and IV Periodontitis; Grades B and C Periodontitis; type 2 Diabetes Mellitus; at least 15 teeth; 30 years and over; males and females
Exclusion criteria
Exclusion criteria: Smokers; pregnant women; lactating women; history of periodontal treatment in the last 6 months; continuous use of oral antiseptics, use of systemic antibiotics, corticosteroids, non-steroidal anti-inflammatory drugs, immunosuppressants, estrogen and estrogen receptor modulators, drugs that can influence the bone metabolism (Alendronate, Calcitonin and others) in the last 6 months; continuous use of medication; need for prophylactic medication for dental treatment (eg mitral valve prolapse); report of allergy to Metronidazole, Amoxicillin (as well as any other penicillin), Aspirin or fish/seafood; use of braces; extensive prosthetic rehabilitations; blood dyscrasias; gastritis or gastric ulcer
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Comparison between the percentage of patients that achieved the endpoint for periodontal treatment and did not achieve the endpoint for periodontal treatment assessed through periodontal clinical examination. | — |
Secondary
| Measure | Time frame |
|---|---|
| Observe probing depth reduction, clinical attachment gain, mean bleeding on probing reduction, and mean plaque index reduction measured through periodontal clinical examination. And glycated hemoglobin levels reduction to assess the impact of periodontal treatment on diabetes control through biclinical exam. | — |
Countries
Brazil
Contacts
Public ContactNidia Castro dos Santos
Universidade Guarulhos
Outcome results
None listed