Coronavirus as a cause of diseases classified in other chapters
Conditions
Interventions
Olfactory training twice a day with four aromas (rose, eugenol citronelal, eucaliptol) for 3 months plus placebo pills (starch) 300mg twice a day for 3 months. (Control group with 64 participants).
Ol
E02.190.888.061
Sponsors
Hospital Universitário Professor Edgard Santos- Universidade Federal da Bahia
Hospital Universitário Professor Edgard Santos- Universidade Federal da Bahia
Eligibility
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: Patients with post-COVID olfaction disorders for more than 3 months; aged between 18 and 65 years; with diagnostic documentation of COVID-19 through a positive test for SARS-CoV-2.
Exclusion criteria
Exclusion criteria: Traumatic brain injury; neurodegenerative and psychiatric illness; pregnancy; allergic rhinitis or other rhinosinusopathy; presence of smell disorder prior to COVID-19; use of topical or systemic corticosteroid therapy in the last 30 days; as well as current use of alpha-lipoic acid; omega 3; vitamin A; zinc or pentoxifylline will be excluded. Patients with a history of smell disorder less than 3 months and all those with previous treatment of the olfactory complaint will also be excluded.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Objective improvement in olfactory function of at least 1 point in the Connecticut olfactory test after 12 weeks of treatment. | — |
Secondary
| Measure | Time frame |
|---|---|
| Subjective improvement of olfactory function through visual analogue scale assessment after 4, 8 and 12 weeks of treatment; olfactory function recovery time; correlation of collected clinical data with olfactory prognosis. | — |
Countries
Brazil
Contacts
Public ContactLorena Figueiredo
Outcome results
None listed