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Impacts of cough-assist machine on success rate of weaning of patients on prolonged mechanical ventilation

Impacts of adding mechanical insufflation-exsufflation on success rate of weaning of patients on prolonged mechanical ventilation

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
REBEC
Registry ID
RBR-10tkvrv6
Enrollment
Unknown
Registered
2024-05-15
Start date
2023-06-01
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Tracheostomy

Interventions

This unicenter, open-label, randomized, controlled pilot study will include 25 patients in mechanical insufflation-exsufflation (MI-E) group and 25 patients in control group. The randomization will be
E02.779

Sponsors

Hospital Universitário da Universidade Federal de Juiz de Fora
Lead Sponsor
Hospital Universitário da Universidade Federal de Juiz de Fora
Collaborator

Eligibility

Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Pacientes aged more than 18 years; mechanical ventilation for more than 21 days; mechanical ventilation through tracheostomy; fulfill criteria for weaning; respiratory stability; hemodynamic stability; uncontrolled infection; no severe mebolic disturb

Exclusion criteria

Exclusion criteria: Pneumothorax; subcutaneous emphysema; pneumomediastinum; thoracic trauma; haemoptysis; intracranial hypertension; readmission to ICU after discharge already tracheostomised; palliative care; refusal to sign the informed consent by the responsible family member

Design outcomes

Primary

MeasureTime frame
To evaluate weaning success rate, defined as withdrawal from mechanical ventilation, characterised by the presence of spontaneous ventilation through the tracheostomy, without connection to the ventilator, during the 24 hours of 5 consecutive days—

Secondary

MeasureTime frame
No secondary outcomes are expected—

Countries

Brazil

Contacts

Public ContactBruno Pinheiro

Hospital Universitário da Universidade Federal de Juiz de Fora

bvallepinheiro@gmail.com+55(32)9977-6584

Outcome results

None listed

Source: REBEC (via WHO ICTRP)