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Use of essential oils for tooth grinding in children with congenital zika virus syndrome

Evaluation of bruxism in children with congenital zika virus syndrome using essential oils

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
REBEC
Registry ID
RBR-10str4px
Enrollment
19
Registered
2026-07-31
Start date
2023-06-30
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Bruxism , zika virus infection , stress Child

Interventions

This is a two-arm, double-blind, randomized controlled clinical trial. A total of 19 participants who meet the eligibility criteria will be randomly assigned by manual lottery allocation. Researchers

Sponsors

Associação unificadda paulista de ensino renovado objetivo
Lead Sponsor
Associação unificadda paulista de ensino renovado objetivo
Collaborator

Eligibility

Age
3 Years to 12 Years

Inclusion criteria

Inclusion criteria: Volunteers with congenital Zika syndrome; both sexes; regardless of race; presence of bruxism characterized by tooth wear

Exclusion criteria

Exclusion criteria: Use of cannabidiol; undergoing any other therapy for bruxism

Design outcomes

Primary

MeasureTime frame
Expected outcome 1: Evaluation of the frequency and severity of bruxism after topical application of essential oil aromatherapy measured by a validated symptom questionnaire at 60 days of follow-up;Observed outcome 1: There was no statistically significant difference in the overall frequency and severity of bruxism between groups after 60 days of follow-up. However, a statistically significant reduction in daytime tooth clenching was observed in the intervention group between pre- and post-therapy (p < 0.035).

Secondary

MeasureTime frame
Expected outcome 1: Evaluation of stress levels through salivary cortisol before and after 60 days of intervention;Observed outcome 1: There was no reduction in mean salivary cortisol levels in the treated group after 60 days of intervention;Expected outcome 2: Evaluation of caregiver satisfaction regarding the assistance received at 60 days of follow-up;Observed outcome 2: A statistically significant difference between groups was observed, with higher caregiver satisfaction in the intervention group regarding the amount of help received (p = 0.006)

Countries

BR

Contacts

Public ContactCristina Ortolani

Universidade Paulista UNIP São Paulo

cristina.ortolani@docente.unip.br+551155864040

Outcome results

None listed

Source: REBEC (via WHO ICTRP) · Data processed: Aug 10, 2026