Tooth loss
Conditions
Interventions
This evaluation proposal is part of a prospective, randomized, controlled, double-blind, split-mouth clinical trial, aimed primarily at assessing clinical, biological, bacteriological, and biomechanic
crestal modules with and without threads (nTh)
crestal module with and without surface treatment (wT) (STUDY 1: different designs of crestal module)
and different levels of implant-abutment platform diameter mismatch (Platform Switching): implants with external hexagon of Ø 4.5 x 13 mm and abutment diameter of 4.5 mm (conventional implant-abutment
Sponsors
Associação Salgado de Oliveira de Educação e Cultura
Centro Universitário do Triângulo
Eligibility
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: Clinically healthy patients; Both genders; Age between 18 to 70; Completely edentulous patients; Dental extractions performed more than 6 months previously
Exclusion criteria
Exclusion criteria: Patients with alcohol, drug or medication abuse; Smokers or those with systemic diseases, such as uncontrolled diabetes; Coagulation disorders; Severe cardiac vascular disorders and other significant illnesses
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| In this study, two comparisons were performed. In study 1, external hexagonal (EH) and Morse taper (MT) connections were compared; crestal modules with and without thread (nTh); crest modulus with and without surface treatment (wT). In study 2, different differences in diameter of the implant-abutment platform (Switching Platform) were evaluated: implants with an external hexagon of Ø 4.5 x 13 mm and an abutment diameter of 4.5 mm (conventional compatible implant-abutment design - CMD), 4.1mm (PS04), 3.8mm (PS07) and 3.3 (PS12). 24 patients underwent surgery, 12 in each group, who received one type of each implant configuration. The primary variable of this study was the peri-implant bone level, and one connection will be considered superior to another when the difference in this parameter was greater than 1 mm. | — |
Secondary
| Measure | Time frame |
|---|---|
| Microbiome and proteomic analysis will describe whether clinical differences are related to differences in microbiological composition and expression of inflammatory markers. Connections with less bone loss are expected to present lower expression of biological mediators of inflammation and a lower presence of anaerobic gram-negative bacteria. | — |
Countries
Brazil
Contacts
Public ContactRoberto Pessoa
Centro Universitário do Triângulo - UNITRI
Outcome results
None listed