Knee osteoarthritis gonarthrosis
Conditions
Interventions
This is a randomized, controlled, three-arm, double-blind clinical study involving 30 volunteers of both sexes, clinically diagnosed with unilateral or bilateral knee osteoarthritis by an orthopedist
Sponsors
Universidade São Francisco
Universidade São Francisco
Eligibility
Age
55 Years to 85 Years
Inclusion criteria
Inclusion criteria: Age between 55-85 years old; have osteoarthritis in the knee joint (unilateral or bilateral) lasting at least 2 years; present pain in at least three of the following actions: going up and down stairs, kneeling, sitting and standing, running, and standing for 2 minutes; a Numerical Pain Scale (NPS) score above 4 points (moderate); and a Kellgren-Lawrence classification of grade IV.
Exclusion criteria
Exclusion criteria: Uncontrolled diabetes mellitus; untreated systemic arterial hypertension; neurological deficits (motor or sensory); history/diagnosis of cancer; fibromyalgia; previous hyaluronic acid injection (and/or invasive therapies); or not accepting participation in the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Expected outcome 1: Assess pain intensity using the numerical pain scale, verified by numerical pain scale ranging from 0 to 10, where 0 corresponds to the absence of pain and 10 to the worst imaginable pain, based on the finding of a variation of at least 20% in pre- and post-intervention measurements. | — |
Secondary
| Measure | Time frame |
|---|---|
| Expected outcome 2: Assess symptoms, pain, joint stiffness, daily activities, sports activities, as well as quality of life using the Knee Injury and Osteoarthritis Outcome Score (KOOS) questionnaire, based on the finding of a variation of at least 30% in pre- and post-intervention measurements.;Expected outcome 3: Assess quality of life using the World Health Organization Quality of Life-bref (WHOQOL-brief) questionnaire, based on the finding of a variation of at least 30% in pre- and post-intervention measurements.;Expected outcome 4: Assess lower limb strength and endurance using the 30-second Sit-to-Stand Test, based on the finding of a variation of at least 10% in pre- and post-intervention measurements.;Expected outcome 5: Assess functional mobility, balance, deambulation capacity, and fall risk in older adults using the Timed Up and Go Test (TUG), based on the finding of a variation of at least 10% in pre- and post-intervention measurements. | — |
Countries
BR
Contacts
Public ContactAndré Sardim
Universidade São Francisco
Outcome results
None listed