Radiotherapy
Conditions
Interventions
The study design will be clinical, controlled, randomized and double blind following the Consort protocol (Consolidated standards of reponting trails) where, for statistical purposes, each alveolus wi
Sponsors
Faculdade de Odontologia da Universidade Federal de Uberlândia
Faculdade de Odontologia da Universidade Federal de Uberlândia
Eligibility
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Patients diagnosed with head and neck cancer; both genders; age above 18 years; with indication and need for pre-radiotherapy tooth extraction and who provide consent to participate in this research project by signing the free and informed consent form
Exclusion criteria
Exclusion criteria: Minor patients; patients who do not agree with the free and informed consent form; patients with advanced tumors who, due to the urgency of starting radiotherapy, do not have enough time to perform tooth extractions; patients with health alterations that contraindicate surgical procedures for tooth extraction
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To evaluate the effect of platelet-rich fibrin combined with deproteinized bovine bone (sticky bone) on the repair process and bone formation in alveoli of pre-irradiated patients. For this, computed tomography scans will be performed after the procedure and radiotherapy, the images will be used to evaluate bone healing after tooth extraction. An analysis of bone density in the region of alveolar repair will be performed by calculating the fractal dimension, where changes in bone microarchitecture will be identified | — |
Secondary
| Measure | Time frame |
|---|---|
| No secondary outcomes expected | — |
Countries
Brazil
Contacts
Public ContactPriscilla Soares
Faculdade de Odontologia - Universidade Federal de Uberlândia
Outcome results
None listed