Mouth mucosa
Conditions
Interventions
This project will be divided into 3 studies with the participation of 90 patients. The studies will be double-blind, randomized, parallel, with 6 arms. In study 1, 30 patients will be allocated into t
AH/CV: Application of hyaluronic acid and green tea gel. In study 2, the 30 patients will be allocated into two groups depending on the type of mouthwash to be used (n = 15 per group): CLX – Use of 0.
AH/CV: Use of hyaluronic acid and green tea mouthwash. In study 3, the 30 patients will be allocated into two groups depending on the type of postoperative care protocol to be used (n = 15 per group):
AH/CV: Use of hyaluronic acid gel and mouthwash and green tea. Healing will be assessed using the MAPS score and a visual analog scale (VAS) for edema, pain, burning, trismus, sensitivity, daily funct
Sponsors
Associação Salgado de Oliveira de Educação e Cultura
Centro Universitário do Triângulo
Eligibility
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: Ages between 18 and 70; patients who requiring dental implants to replace one or more teeth
Exclusion criteria
Exclusion criteria: Patients who are heavy smokers (More than 20 cigarettes per day); patients with uncontrolled diabetes (glycated hemoglobin above 8%); patients who are pregnant or breastfeeding; who do not agree to return for follow-u; and who have used corticosteroids; chemotherapy; and immunomodulators in the last 3 months
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary variable in this study will be the evaluation of peri-implant healing using the MAPS score. It is expected that patients using the green tea and hyaluronic acid gel and mouthwash will show less than a 10% difference in the analysis of tissue healing around dental implants using the MAPS score compared to patients using chlorhexidine-based mouthwashes and gels | — |
Secondary
| Measure | Time frame |
|---|---|
| Patients using green tea and hyaluronic acid gel and mouthwash will experience less than a 10% difference in edema, pain, burning, trismus, sensitivity, daily function, chewing, swallowing, taste, smell, taste alteration, and pigmentation, as assessed by the VAS scale, compared to patients using chlorhexidine-based mouthwashes and gels;Patients using green tea and hyaluronic acid gel and mouthwash will have less than a 10% difference in the assessment of biological markers of inflammation as evaluated by the ELISA test compared to patients using chlorhexidine-based mouthwashes and gels. | — |
Countries
Brazil
Contacts
Public ContactRoberto Pessoa
Centro Universitário do Triângulo - UNITRI
Outcome results
None listed