Wounds and Injuries
Conditions
Interventions
This is a five-arm, blind, randomized controlled clinical study. A total of 100 people who meet the eligibility criteria. Experimental group: 20 participants of both sexes, aged over 18, will be rando
E07.206.627
Sponsors
Universidade Federal de Alagoas
Universidade Federal de Alagoas
Eligibility
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Minimum age of 18 years. Volunteers with chronic venous injury using unna boot compression or elastic therapy. Surface area up to 150 cm2. Wound covered with > 50% granulation tissue, no black necrotic tissue on the wound surface, and spaced > 3cm from any wound edge to another wound located on the same limb. Both genders. Variable nutritional status and hydration. They may carry the most varied clinical pathologies
Exclusion criteria
Exclusion criteria: Hypersensitivity to one of the dressing components, poor health, body mass index (BMI) in the grade 3 obesity range, erysipelas, cellulitis, lymphangitis, chronic lymphedema. Malignant wound degeneration or neoplastic lesion treated by radiotherapy, chemotherapy and immunosuppressive drugs or corticosteroid dose. Clinically infected lesion requiring a systemic antibiotic. History of deep or superficial venous thrombosis in the previous three months. Have undergone surgery directly related to venous insufficiency within two months prior to inclusion. Wound surgery planned during the trial period. Patients who are in the terminal phase will not be included in the study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Evaluate the healing of chronic wounds with the use of bioactive dressings containing polycaprolactone, propolis extract or wax. Using the Anova test method with post hoc (Tukey) HSD or Kruskal-Wallis Test with Dunn post hoc depending on the homoscedasticity of the variables | — |
Secondary
| Measure | Time frame |
|---|---|
| Assess the pain in the wound. Using the visual analogue scale (VAS);Expected to find a decrease in wound exudate | — |
Countries
Brazil
Contacts
Public ContactAlba Thomé
Universidade Federal de Alagoas
Outcome results
None listed