Weight loss
Conditions
Interventions
All the 66 patients will be submitted to endoscopic exams, which will be performed at HB in São José do Rio Preto, with patients on fasting for at least 8 hours. With the patient in the left lateral p
Sponsors
Faculdade de Medicina de São Jose do Rio Preto
Faculdade de Medicina de São Jose do Rio Preto
Eligibility
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: The study will include patients undergoing Roux-en-Y gastric bypass and who, after 24 months of the procedure, presented weight relapse> 10% of the weight lost. In addition, participants must be over 18, of both sexes and of any ethnicity.
Exclusion criteria
Exclusion criteria: Exclusion criteria will be considered for patients under 18; those who do not accept or are not able to perform the endoscopy exam (s) and follow-up during the study; who abandon the study during its realization; with a history of liver disease with cirrhosis or chronic active hepatitis; anticoagulated or with known clotting disorders; pregnant women who became pregnant during the study period, or intend to become pregnant during the study; patients who are participating in other similar studies; severe malnourished, anemic, chronic alcohol users or drug users; patients allergic to sedatives used during the endoscopic procedure; with a history of recent neoplasia (after reduction surgery); HIV-positive; reoperated with bariatric surgeries or for similar purposes performed before or after the study surgery; with immediate or late postoperative complications that required further surgery; patients who underwent a surgical technique other than gastric bypass with Roux-en-Y reconstruction without placing the Silastic ring.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The analysis after 30 days (short term) showed a significant reduction in weight, excess weight and weight relapse between the group submitted to argon plasma ablation and the Control Group (p <000.1, for all variables). In this case, of the 38 patients submitted to APA (EG), 37 (97.3%) presented weight loss and one patient maintained weight during this period. The maximum weight loss was 11 kg, and the minimum loss was 1 kg, reaching a PP of 4.8 ± 2.7 kg,% PEP of 22.8 ± 33.7%,% PTP of 4.8 ± 2, 4% and RPR of 46.5 ± 34.4%. However, in the Control Group, of the 28 patients evaluated in the same period of 30 days (short term), 67.8% (N = 19) presented weight loss, 10.7% (N = 3) maintained their initial weight and 21, 4% (N = 6) gained weight. The maximum loss was 6 kg, the minimum 1 kg and the maximum gain of 2 kg in the period, with an average value for PP of 1.6 ± 2.0 kg,% PEP of 9.3 ± 13.9%, % PTP of 1.8 ± 2.2% and RPR of 17.1 ± 21.0% after 30 days (short term). The other periods, such as 60, 90 and 120 days, maintained the significant result of PP,% PEP,% PTP and RPR between CG and GE (p <000.1, for all variables). ;One year after the beginning of the follow-up (long term), the final analysis of the weight did not show any difference between the groups studied (p = 0.964). However, values for% PEP and% PTP were higher in the Study Group than in the Control Group (p = 0.038; p = 0.045, respectively). Of the 38 patients in the Study Group, 86.8% (N = 33) attended a one-year return visit, of these, 72.7% (N = 24) gained weight after the process, 21.2% (N = 7) lost weight and 6.0% (N = 2) maintained weight. They started the study with an average weight of 98.5 ± 21.2 kg, reaching 86.0 ± 13.2 kg after 90 days of PAC, returning to an average weight of 94.2 ± 21.6 kg after one year of discharge (long term), corresponding to an average value for PP of 1.5 ± 5.5 kg,% PEP of 15.1 ± 61.3%,% PTP of 1.8 ± 5.7% and RPR of 21.9 ± 62.9%. | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary outcomes are not expected;Secondary outcomes are not expected | — |
Countries
Brazil
Contacts
Public ContactGustavo Gurian
Outcome results
None listed