Lung Diseases
Conditions
Interventions
There are two endurance tests, one with a high-flow nasal cannula and the other with a Venturi mask, which are scheduled seven days apart. Due to the cross design, all twelve participants receive thes
high-flow nasal cannula (total gas flow = 50 l/min, FiO2 = 50%) with a humidifier, snugly fitted to the nostrils and secured with an elastic band. Before performing the test, the participant remains w
Sponsors
Hospital de Messejana Dr Carlos Alberto Studart Gomes
Hospital de Messejana Dr Carlos Alberto Studart Gomes
Eligibility
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Lung transplant candidates; both genders; older than 18 years; in initial evaluation for inclusion in a pulmonary rehabilitation program; with oxygen dependency or need for oxygen supplementation during the symptom-limited incremental load test performed before inclusion in the study
Exclusion criteria
Exclusion criteria: Candidates who did not comply with the protocol, because they were absent on the assessment day; candidates who did not present clinical conditions on the day of the test
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Outcome found 1: A difference of 357 s (95% confidence interval – CI 181 – 533 s; p = 0.001) was found in exercise tolerance between the time achieved in the endurance test performed with the high-flow nasal cannula (937 s, 95% CI 668 – 1205 s) and the time achieved in the endurance test performed with the Venturi mask (580 s, 95% CI 403 – 756 s).;Expected outcome 1: It is expected to find a difference of at least 109 seconds in exercise tolerance between the time achieved in the endurance test performed with the high-flow nasal cannula and the time achieved in the endurance test performed with the Venturi mask. | — |
Secondary
| Measure | Time frame |
|---|---|
| Expected outcome 2: Absence of difference in the comparison of changes between pre- and post-endurance test, in physiological variables such as symptoms of dyspnea and lower limb fatigue, respiratory rate, peripheral oxygen saturation, heart rate, blood pressure and peripheral blood lactate level , between the two oxygen systems (high-flow nasal cannula and Venturi mask).;Outcome found 2: There was no statistically significant or clinically important difference in the comparison of changes between pre- and post-endurance test, in physiological variables such as symptoms of dyspnea and lower limb fatigue, respiratory rate, peripheral oxygen saturation, heart rate, blood pressure and peripheral blood lactate level, between the two oxygen systems (high-flow nasal cannula and Venturi mask). | — |
Countries
Brazil
Contacts
Public ContactEmilia Rocha
Hospital de Messejana Dr Carlos Alberto Studart Gomes
Outcome results
None listed