Surgical site infecction
Conditions
Interventions
This is a controlled non-randomized clinical trial with 50 to 100 volunteers per group, divided into 3 groups which will receive the following regimens: Group A (control)-no antibiotic, Group B-Amoxi
Sponsors
Faculdade de Odontologia da Universidade Federal de Uberlândia
Hospital Odontológico da Faculdade de Odontologia da Universidade Federal de Uberlândia
Eligibility
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Volunteers aged 18 and over; both genders; with at least 1 mandibular third molar to be extracted under local anesthesia - indications for extraction in this study will be any third molar, impacted or not, with or without limited space for eruption, or extraction indicated for any other reason in accordance with the criteria from the Oral and Maxilo Facial Surgery Department (CTBMF)
Exclusion criteria
Exclusion criteria: Age under 18; poor oral conditions; pregnant women; systemic illnes; inflammation or infection at the extraction sites; current use of other antibiotic therapy; immunosuppression; gastrointestinal bleeding or ulceration; cardiovascular and kidney diseases; and any allergies to the local anesthetic (Alphacaine 100, DFL, Brazil - 2% Lidocaina HCl with 1:100,000 Epinephrine); Nimesulide or other nonsteroidal anti-inflammatory drugs
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Evaluating the infection level after third molars extraction by using different medicin terapeutics in the experimental groups; from data listed in the Formulary I evaluations will be made within and/or among the groups; unnecessary use of antibiotic prophylaxis before or after surgical proceeding is expected; statistical analysis with 5% confidence level will be performed | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondery effects are not expected | — |
Countries
Brazil
Contacts
Public ContactRoberto Campos
Faculdade de Odontologia da Universidade Federal de Uberlândia
Outcome results
None listed