Dietary Fiber. Gestational Diabetes
Conditions
Interventions
A randomized clinical trial will be carried out with patients with GDM treated at the High-Risk Pregnancy Outpatient Clinic of the University Hospital HU/UFSC/EBSERH. Inclusion Criteria: Adult patient
Control Group - CG). GPDX patients will receive sachets containing 10g of polydextrose for 8 weeks. For both groups, food consumption, anthropometric measurements, composition of the intestinal microb
Sponsors
Universidade Federal de Santa Catarina
Hospital Universitário Polydoro Ernani de São Thiago - HU/UFSC/EBSERH
Eligibility
Sex/Gender
Female
Age
19 Years to No maximum
Inclusion criteria
Inclusion criteria: Adult patients over 19 years of age, with GDM diagnosed between 24 and 28 weeks of gestation by OGTT, who have a eutopic pregnancy, with only one embryo and who accept and sign the Informed Consent Form (TCLE).
Exclusion criteria
Exclusion criteria: Exclusion Criteria: Alcoholism, alcoholism, drug use, presence of fetal malformations, psychiatric, neurological, autoimmune, renal, hepatic diseases, inflammatory bowel diseases, previous type 1 or 2 Diabetes Mellitus, immunodeficiencies, allergies or food intolerances, hyperemesis gravidarum, use of anti-inflammatory drugs in the last 30 days and use of antibiotics and supplements or complements containing pre, pro or synbiotics in the last 90 days.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| It is expected that the consumption of polydextrose can help with glycemic homeostasis in patients with Gestational Diabetes Mellitus | — |
Secondary
| Measure | Time frame |
|---|---|
| It is expected that the consumption of polydextrose can bring positive effects on the intestinal microbiota of patients with GDM, modifying its composition based on genera and/or species of bacteria capable of helping to regulate energy metabolism, thus contributing to the reduction of the inflammatory process. subclinical and oxidative stress observed in this population. | — |
Countries
BR
Contacts
Public ContactLaboratório HU/UFSC/EBSERH
Hospital Universitário Polydoro Ernani de São Thiago - HU/UFSC/EBSERH
Outcome results
None listed