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Salivary, psychosocial, and dental assessment of transgender individuals in the Paraíba Valley region (São Paulo)

Assessment of saliva, oral health and mental health in a transgender population of a region in São Paulo state.

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
REBEC
Registry ID
RBR-10d9ks6b
Enrollment
25
Registered
2026-03-11
Start date
2025-01-01
Completion date
Unknown
Last updated
2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Transgender persons

Interventions

This is a cross-sectional observational study (n=100), in which the population will be divided equally into four groups: 1) MTrans: transgender women
2) HTrans: transgender men
3) MCis: cisgender women
4) HCis: cisgender men. The objective is to evaluate and understand in a multidimensional way the oral and mental health profile of transgender people in Vale do Paraíba, São Paulo, Brazil (SP), ident
II. Smoking profile
III. Smoking burden
IV. Alcohol profile. Through clinical dental examinations, information on oral health will be collected, including ICDAS and completion of a periodontal chart. Next, a psychosocial assessment will be

Sponsors

Instituto de Ciência e Tecnologia de São José dos Campos - UNESP
Lead Sponsor
Universidade Federal de São Paulo, Campus São José dos Campos
Collaborator
Universidade do Vale do Paraíba (UNIVAP)
Collaborator

Eligibility

Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Transgender women (WTrans) Group: self-identified transgender women, undergoing gender transition and who at the time of data collection may or may not be undergoing hormone therapy; Transgender men (MTrans) Group: self-identified transgender men, undergoing gender transition and who at the time of data collection may or may not be undergoing hormone therapy; Cisgender women (MCis) Group: self-identified cisgender women; Cisgender men (HCis) Group: self-identified cisgender men; Aged 18 years or older; Availability to participate in the research

Exclusion criteria

Exclusion criteria: Individuals under 18 years of age; Inability to provide signed consent to participate in the research; Individuals with systemic conditions that may interfere with the research results, at the researchers' discretion

Design outcomes

Primary

MeasureTime frame
We will observe the periodontal health status of transgender patients through Clinical Insertion Level and Probe Bleeding measurements, obtained by completing a periodontal chart. In addition, we will explore possible correlations between periodontal status and salivary proteomic profile through proteomics. In turn, we will use the ELISA method, WHOQOL-short and DASS-21 to correlate salivary levels of cortisol, chromogranin A, and DHEA with levels of quality of life and anxiety, stress, and depression. We hope to contribute to the knowledge about saliva as a diagnostic tool for oral and systemic conditions in transgender people in a multidisciplinary context. To date, there are few published studies on oral and mental health involving the target group, as well as on the use of saliva as a means of investigating oral disorders and the possible influence of gender-affirming hormones. Thus, we believe that this project has the potential to impact the technical-scientific and translational development of the subject.

Secondary

MeasureTime frame
No secondary outcomes are expected.

Countries

BR

Contacts

Public ContactVictoria Oliveira

Universidade Estadual Paulista

victoria.gb.oliveira@unesp.br+55-12-39479079

Outcome results

None listed

Source: REBEC (via WHO ICTRP) · Data processed: Apr 4, 2026