Periodontal Diseases
Conditions
Interventions
This is a cross-sectional observational study. Individuals were selected from the population seeking dental care at the Ribeirão Preto School of Dentistry - FORP/USP. Seventy-two individuals were sele
Sponsors
Universidade de São Paulo
Faculdade de Odontologia de Ribeirão Preto da Universidade de São Paulo
Eligibility
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: All individuals must be systemically healthy; of either gender; at least 18 years old; have at least 15 natural teeth, excluding third molars and teeth indicated for extraction; and be willing to adhere to the study protocol. In the Periodontal Health group: absence of attachment loss and bone loss due to periodontitis; probing depth (PD) up to 3 mm at all sites and bleeding on probing (BOP) at no more than 10% of sites throughout the entire oral cavity. For the Gingivitis group: presence of generalized gingivitis, with more than 30% of the sites in the whole mouth showing BOP; all sites with PD up to 3 mm and absence of attachment loss and bone loss due to periodontitis. In the Periodontitis group: presence of generalized stage III periodontitis, grades B or C, with at least 30% of the teeth having at least one site with PD and Clinical Attachment Level (CAL) = 5 mm and BOP
Exclusion criteria
Exclusion criteria: Use of antibiotics, probiotics, and/or prebiotics in the last six months; undergoing periodontal treatment in the last six months; continuous use of mouthwashes containing antimicrobial agents; long-term use of anti-inflammatory or immunosuppressive medication; any systemic involvement that may interfere with the onset and/or progression of periodontal diseases; chronic gastrointestinal diseases; extensive prosthetic involvement; need for antibiotic prophylaxis for routine dental procedures; smoking; pregnancy; lactation
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The study aims to characterize the periodontal and fecal microbiomes of volunteers who are periodontally healthy, those with gingivitis (G), and those with periodontitis (PE) (stage III, grades B or C generalized). It also seeks to evaluate the interrelationship between these two microbiomes across the three conditions presented by the volunteers. | — |
Secondary
| Measure | Time frame |
|---|---|
| The study aims to correlate the periodontal and fecal microbiomes with clinical, sociodemographic, and lifestyle parameters. | — |
Countries
Brazil
Contacts
Public ContactFlávia Aparecida Furlaneto
Universidade de São Paulo
Outcome results
None listed