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Use of Platelet-Rich Plasma and Low-Level Laser to improve Skin Lesions caused by Psoriasis

Effects of the combination of Platelet-Rich Plasma and Low-Level Laser Therapy on Psoriasis-Related Skin Lesions: a case study

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
REBEC
Registry ID
RBR-10bbr596
Enrollment
Unknown
Registered
2025-09-30
Start date
2025-08-21
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Psoriasis

Interventions

This is a single-case, blinded study involving one participant, to be conducted by the Laboratory of Biomaterials and Tissue Engineering (LABETEC), located in the Department of Biosciences at the Fede
E02.774

Sponsors

Universidade Federal de São Paulo
Lead Sponsor
Departamento de Biociências -Baixada Santista - Universidade Federal de São Paulo
Collaborator

Eligibility

Sex/Gender
Female
Age
40 Years to 45 Years

Inclusion criteria

Inclusion criteria: Confirmed diagnosis of psoriasis. A female patient aged between 40 and 45 years. Presence of lesions localized on the lower limbs. Overall satisfactory health status, without severe comorbidities that interfere with the evaluation and treatment of psoriasis. Confirmed diagnosis of psoriasis with lesion extent greater than 1 and severity index greater than 1, defined by the Psoriasis Area and Severity Index (PASI) score obtained during the initial evaluation conducted by the study researchers. At least four weeks without the use of topical corticosteroids or other local therapies in the treatment area

Exclusion criteria

Exclusion criteria: Presence of other dermatological conditions. Immunological or severe comorbidities. History of severe allergic reactions to any component of the treatments used in the study. Use of medications that interfere with the study. Inability to attend regular follow-up

Design outcomes

Primary

MeasureTime frame
To investigate the effects of the association of a photobiomodulation (PBM) protocol combined with platelet-rich plasma (PRP) for the reduction of psoriasis lesions, analyzing the following variables: decrease in lesion area and severity, reduction in plaque thickness and local inflammation, and improvement in skin quality of a woman with psoriasis through photographic images and the Psoriasis Area and Severity Index (PASI) questionnaire—

Secondary

MeasureTime frame
To evaluate the improvement in the quality of life of a patient with psoriasis using the photobiomodulation (PBM) protocol combined with platelet-rich plasma (PRP) through the Short Form 36 Health Survey (SF-36) questionnaire—

Countries

Brazil

Contacts

Public ContactThatiane Santos

Universidade Federal de São Paulo - Campus Baixada Santista

thatiane.i.ribeiro@hotmail.com+55(13) 32218058

Outcome results

None listed

Source: REBEC (via WHO ICTRP)