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Influence of different products on the effectiveness and duration of treatment of sensitive teeth and patients' well-being

Influence of different topical desensitizing medications on the effectiveness and durability of treatment of dentin hypersensitivity and quality of life of patients

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
REBEC
Registry ID
RBR-109h3wcv
Enrollment
Unknown
Registered
2024-05-02
Start date
2024-03-15
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Dentin sensitivity

Interventions

This is a three-arm, double-blind, randomized controlled clinical study. 33 individuals will be selected (each individual with at least 3 sites to be treated), according to inclusion and exclusion cri
Experimental group 1: 3% potassium nitrate gel + glutaraldehyde + universal adhesive system (2 layers)
Experimental group 2: 3% potassium nitrate gel + glutaraldehyde + universal adhesive system (2 layers) + fluid resin. Both the researchers who will evaluate the outcomes and the participants will not

Sponsors

Universidade Federal de Uberlândia
Lead Sponsor
Universidade Federal de Uberlândia
Collaborator

Eligibility

Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: Patients with dentin hypersensitivity in at least 3 teeth with loss of tooth structure of less than 1mm; moderate to severe dentin hypersensitivity (pain greater than 3); Individuals who are interested in the treatment of dentin hypersensitivity; agree to participate and sign the free and informed consent form; participants aged between 18 and 60

Exclusion criteria

Exclusion criteria: Presence of dentin sensitivity caused by the presence of caries or unsatisfactory restorations; patient undergoing orthodontic or periodontal treatment; patients undergoing teeth whitening; presence of spontaneous pain in the tooth with dentin hypersensitivity, characterizing pulpitis; presence of periodontal disease; poor and unsatisfactory oral hygiene; use of extensive prostheses; patients with severe bruxism and changes in vertical dimension; patients with uncontrolled gastroesophageal reflux disease; patients with uncontrolled systemic or psychological illnesses; patients who use controlled medications that interfere with salivary flow; pregnant and lactating women; smokers

Design outcomes

Primary

MeasureTime frame
It is expected that the universal adhesive system and flow resin as obliterating agents improve the effectiveness and durability of the treatment of dentin hypersensitivity when compared to the use of potassium nitrate associated with glutaraldehyde, control group

Secondary

MeasureTime frame
Evaluate the periodontal condition of patients, determined through clinical assessment before the intervention and within 7, 30, 90 and 180 days for follow-up;Evaluate patients' quality of life, determined through the quality of life questionnaire, before the intervention and within 90 and 180 days for follow-up

Countries

Brazil

Contacts

Public ContactJúlia Martins

Universidade Federal de Uberlândia

juliamartins0807@gmail.com+55 (034) 3225-8116

Outcome results

None listed

Source: REBEC (via WHO ICTRP) · Data processed: Mar 2, 2026