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Effect of a 35% hydrogen peroxide gel containing a composite in reducing of tooth sensitivity after in-office dental bleaching

Effect of the use of a 35% hydrogen peroxide gel containing capsaicin and hydroxyapatite nanoparticles to reduce post-bleaching tooth sensitivity

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
REBEC
Registry ID
RBR-1083qqwy
Enrollment
Unknown
Registered
2023-08-10
Start date
2023-07-20
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Dentin sensitivity

Interventions

It will be a split-mouth study. A randomization list will be generated at www.sealedenvelope, and randomization blocks with sizes of 2 and 4 will be used, with equal chances regarding group allocation
D02.455.326.271.690.222

Sponsors

Universidade Estadual de Ponta Grossa - UEPG
Lead Sponsor
Universidade Estadual de Ponta Grossa
Collaborator

Eligibility

Age
18 Years to 50 Years

Inclusion criteria

Inclusion criteria: Patients aged between 18 and 50 years; both genders; with good oral and general health; have their maxillary anterior teeth free from restorations and carious lesions; canines with color A2 or darker according to the Classical Vita scale (Vita Zahnfabrik, BadSäckingen, Germany); to agree with the free and informed consent form

Exclusion criteria

Exclusion criteria: Patients who have already performed dental whitening; pregnant patients or lactating; severe browning (staining by tetracycline; fluorosis or endodontics); people with dental prostheses and orthodontic appliances and any other oral pathology; patients who have gastric, heart, kidney and liver problems; diabetes; hypertension; who are making continuous use of drugs with analgesic and anti-inflammatory action

Design outcomes

Primary

MeasureTime frame
Expected outcome: It is expected to find a reduction in tooth sensitivity after using the experimental whitening gel containing the composite, at some point up to 48 hours after each session, by using the VAS visual analog scale (0 to 10). Percentage of patients with pain will be called absolute risk of tooth sensitivity.

Secondary

MeasureTime frame
Expected outcome: It is expected to find a reduction in the intensity of tooth sensitivity after using the experimental whitening gel containing the composite, at some point up to 48 hours after each session, by using the VAS visual analog scale (0 to 10). Percentage of patients with pain will be called absolute risk of tooth sensitivity. Values will be presented as mean and standard deviation;Expected outcome: The color difference between the two groups is expected to be effective, assessed at baseline and 1 month after bleaching by means of the Viita Classical scales and the Bleachedguide Vita shade guide, as well as with the Vita Easyshade spectrophotometer. Data will be presented as means and standard deviations

Countries

Brazil

Contacts

Public ContactPaulo Farago

Universidade Estadual de Ponta Grossa

pvfarago@gmail.com+55(42)32203102

Outcome results

None listed

Source: REBEC (via WHO ICTRP)