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Acute effects of breaking sedentary behavior with isometric squat on blood pressure, cardiac autonomic modulation, and cognitive function in hypertensive individuals during the workday

Acute effects of breaking sedentary behavior with isometric squatting on blood pressure, cardiac autonomic modulation, and cognitive function in hypertensive individuals during the workday: a randomized crossover trial

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
REBEC
Registry ID
RBR-1082sd5r
Enrollment
Unknown
Registered
2025-11-26
Start date
2025-09-28
Completion date
Unknown
Last updated
2025-12-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Blood pressure, Sedentary Behavior, Cognition, Hypertension

Interventions

This is a randomized crossover clinical trial with two experimental sessions: a session of breaking sedentary behavior with isometric wall squat exercise and a control session. Due to the crossover de

Sponsors

Universidade Federal Rural de Pernambuco
Lead Sponsor
Universidade Federal Rural de Pernambuco
Collaborator

Eligibility

Age
30 Years to 59 Years

Inclusion criteria

Inclusion criteria: Adults with hypertension; aged 30 to 59 years; perform administrative work while seated for more than 6 hours per day; no musculoskeletal problems in the lower limbs that prevent squatting or standing; no cardiac or cerebrovascular diseases; not using insulin; perform occupational activities in a workplace with adequate physical infrastructure; wear flat shoes suitable for performing the interventions

Exclusion criteria

Exclusion criteria: Individuals who do not complete the protocol of the break or control sessions; transferred to another position or function that changes the characteristics of the occupational activity; choose not to participate in the study

Design outcomes

Primary

MeasureTime frame
It is expected to find a difference of -4 mmHg in home systolic and diastolic blood pressure, assessed by the oscillometric method, after a single session of breaking up sedentary behavior with isometric wall squat exercise, based on a statistically significant session and time interaction (P<0.05)

Secondary

MeasureTime frame
It is expected to find a 20% improvement in executive function, as assessed by the Stroop Test, after a single session of breaking up sedentary behavior with isometric wall squat exercise, based on a statistically significant session and time interaction (P<0.05);It is expeted to find a 20% improvement in cognitive flexibility, as measured by the Trail Making Test (Parts A and B), after a single session of breaking up sedentary behavior with isometric wall squat exercise, based on a statistically significant session-by-time interaction (P<0.05);It is expeted to find a 20% improvement in cardiac autonomic modulation, assessed by heart rate variability analysis, after a single session of breaking up sedentary behavior with isometric wall squat exercise, based on a statistically significant session-by-time interaction (P<0.05)

Countries

Brazil

Contacts

Public ContactBreno Farah

Universidade Federal Rural de Pernambuco

breno.farah@ufrpe.br+55(81)99709-0012

Outcome results

None listed

Source: REBEC (via WHO ICTRP)