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Effect of chemicals containing Green Tea extract and Hyaluronic Acid on toothpastes and mouthwashes on the clinical and microbiological aspects of people using orthodontic appliances.

Effect of chemical agents containing Green Tea extract and Hyaluronic Acid, in toothpaste and rinse formulations, on clinical and microbiological parameters of individuals with orthodontic appliances

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
REBEC
Registry ID
RBR-106z4g6c
Enrollment
Unknown
Registered
2025-11-07
Start date
2024-12-01
Completion date
Unknown
Last updated
2025-11-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Dental Plaque

Interventions

This is a double-blind, randomized controlled clinical trial. 57 patients with generalized gingivitis were invited to participate in this study and were randomly allocated to the group. Randomization

Sponsors

Universidade de São Paulo
Lead Sponsor
Universidade de São Paulo
Collaborator

Eligibility

Age
12 Years to 30 Years

Inclusion criteria

Inclusion criteria: Individuals between twelve and thirty years of age; both genders; undergoing treatment with fixed orthodontic appliances in orthodontics specialization clinics at the Faculty of Dentistry of Ribeirão Preto; having a case of generalized gingivitis

Exclusion criteria

Exclusion criteria: Presenting systemic compromise; smoking; using drugs or controlled medication; having used mouthwashes with antimicrobial solutions for up to three months before the start of the research; using antibiotics for up to six months before the start of the research; not having used anti-inflammatory drugs in the seven days preceding the start of the research or using them during the research; patients who had undergone dental cleaning in the last six months

Design outcomes

Primary

MeasureTime frame
To evaluate the effect of toothpaste containing green tea extract and hyaluronic acid in plaque accumulation and gingival bleeding.

Secondary

MeasureTime frame
To evaluate the effect of toothpaste containing green tea extract and hyaluronic acid in relation to clinical parameters as Probing Depth, Bleeding on Probing and Clinical Attachment Level and microbiological and post-treatment signs and symptoms

Countries

Brazil

Contacts

Public ContactMilenna Fuly

Universidade de São Paulo

millefuly@gmail.com+55-21-97264-9117

Outcome results

None listed

Source: REBEC (via WHO ICTRP)