Growth and differentiation Factor-15
Conditions
Interventions
We measured GDF-15 at hospital admission in 50 patients hospitalized for atrial fibrillation in 2 private hospitals at the city of Niterói, and we observed the occurrence of mortality, thrombosis and
V03.175.500
Sponsors
Universidade Federal Fluminense
Universidade Federal Fluminense
Eligibility
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Hospitalized patients with a primary or secondary or secondary diagnosis of acute, paroxysmal or permanent Atrial Fibrillation; aged 18 years or older.
Exclusion criteria
Exclusion criteria: Presence of associated terminal disease (malignant neoplasms or others); pregnancy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Expected outcome 1: It is expected to find an increase in the number of all-cause mortality events within a year, using the Kaplan-Meyer survival analysis method, especially in patients with biomarker values ??above the median found in the study.; Primary Outcome found: We found 7 deaths during the follow-up. These results will still be submitted to statistical analysis. | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary Outcome found 3: We FOUND 6 hospital readmissions due to atrial fibrillation or heart failure during the follow-up period. These results will still be submitted to statistical analysis.;Expected secondary outcome 1: It is expected to find an increase in the number of stroke or systemic embolism events, assessed by clinical diagnosis and complementary imaging exams, in the period of one year, using the Kaplan-Meyer analysis method, especially in patients with biomarker values ??above the median. ;Expected secondary outcome 2: It is expected to find an increase in the number of major bleeding events, according to ISTH criteria, in a one-year period, using the Kaplan-Meyer analysis method, especially in patients with biomarker values above the study median. ;Expected secondary outcome 3: It is expected to find an increase in the number of events of new hospitalization due to atrial fibrillation or heart failure, in the period of one year, verified using the Kaplan-Meyer analysis method, especially in patients with biomarker values ??above the study median. ;Expected secondary outcome 4: It is expected to find an increase in the number of death events due to cardiovascular causes, in the period of one year, using the Kaplan-Meyer analysis method, especially in patients with biomarker values ??above the study median. ;Secondary Outcome found 1: We found no embolic new events after the 1-year follow-up period These results will still be submitted to statistical analysis.;Secondary Outcome found 2: There was 1 major bleeding event after the 1-year follow-up period; These results will still be submitted to statistical analysis.;Secondary Outcome found 4: We FOUND 4 deaths due to cardiovascular causes during the follow-up. These results will still be submitted to statistical analysis. | — |
Countries
Brazil
Contacts
Public ContactAngelo di Candia
Universidade Federal Fluminense
Outcome results
None listed