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The effects of light therapy on the cognitive processes (attention and memory) of healthy subjects

The cognitive effects of Transcranial Photobiomodulation Therapy (PBMt) in healthy subjects: a randomized, double-blind, placebo-controlled clinical trial

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
REBEC
Registry ID
RBR-104pstbt
Enrollment
Unknown
Registered
2025-11-10
Start date
2025-08-25
Completion date
Unknown
Last updated
2025-11-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Prepulse Inhibition

Interventions

The Light Emitting Diode (LED) device will have 54 850nm diodes, with a total irradiated area of 54cm². The study will be conducted with eligible university students, randomly assigned to two groups:

Sponsors

Sociedade de Educação Superior e Cultura Brasil S.A.
Lead Sponsor
Sociedade de Educação Superior e Cultura Brasil S.A.
Collaborator

Eligibility

Age
18 Years to 25 Years

Inclusion criteria

Inclusion criteria: Be a regular student of the UNISUL medical course; both sexes; be between 18 and 25 years old

Exclusion criteria

Exclusion criteria: Not signing the TCLE; having a history of or current epileptic episodes; being pregnant or lactating; being an oncology patient

Design outcomes

Primary

MeasureTime frame
It is expected to find improvement in inhibitory control after the transcranial photobiomodulation intervention, verified using the Stroop Test Victoria Version, based on the comparison of reading times of three cards with 24 items each before and after the intervention, with improvement being defined as a reduction in total reading time, especially on the third card which evaluates cognitive interference

Secondary

MeasureTime frame
It is expected to find improvement in attentional processes after the transcranial photobiomodulation intervention, verified using the Trail Making Test Parts A and B, based on the comparison of execution times for parts A and B before and after the intervention, with improvement being defined as a reduction in total execution time, especially in part B which requires greater executive function demands;It is expected to find improvement in short-term and working memory after the transcranial photobiomodulation intervention, verified using the Digit Span subscale of the Wechsler Adult Intelligence Scale – WAIS III, with improvement defined as an increase in the total number of correctly recalled digit sequences in both forward and backward order, with a maximum possible score of 32 points ;It is expected to find improvement in controlled attention, inhibition of automatic responses, and cognitive flexibility after the transcranial photobiomodulation intervention, verified through the application of the neuropsychological Five Digit Test, with improvement defined as a reduction in execution time in the Choice and Alternation phases compared to pre-intervention performance

Countries

Brazil

Contacts

Public ContactDaniel Martins

Universidade do Sul de Santa Catarina

danielmartinsfisio@hotmail.com+55-48-999185021

Outcome results

None listed

Source: REBEC (via WHO ICTRP)