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Use of the muscle relaxant Rocuronium in abdominal surgeries by video: comparison between small fractioned doses and continuous infusion

Use of Rocuronium in elective Videolaparoscopic surgeries: comparison between bolus administration and continuous infusion

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
REBEC
Registry ID
RBR-104b9shm
Enrollment
Unknown
Registered
2024-01-22
Start date
2024-03-01
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Muscle Tension, Laparoscopy

Interventions

This will be a single-blind randomized clinical trial. The number of patients included will be 60. The patient will be admitted to the Surgical Center of the Agudos Block and will be approached by the
B=bolus administration). He will also prepare the rocuronium infusion or bolus dose according to the group. The team's anesthesiologist will initiate denitrogenation with 100% oxygen, as usual, and wi

Sponsors

Hospital Central do Exército
Lead Sponsor
Hospital Central do Exército
Collaborator

Eligibility

Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Adults over 18 years old; both sexes; ASA I, II and III - Anesthetic risk classification according to the American Society of Anesthesiologists [ASA1 (patient without comorbidities), ASA 2 ( patient with compensated comorbidities, without functional limitations), ASA 3 (patient with decompensated comorbidities with mild functional limitation.)]; surgery expected to last more than 1 hour

Exclusion criteria

Exclusion criteria: Known allergy to Rocuronium and/or Sugammadex; prior extensive surgery in the surgery cavity; locomotor or neurological disease; gestation; kidney or liver failure; refusal by the patient or his guardian; concomitant use of drugs that are known to interact with Rocuronium according to the manufacturer's package leaflet

Design outcomes

Primary

MeasureTime frame
To compare the total dose of rocuronium used to maintain deep muscle relaxation in intermittent bolus and continuous infusion techniques in laparoscopic surgeries

Secondary

MeasureTime frame
Secondary outcomes are not expected

Countries

Brazil

Contacts

Public ContactDayse Rodrigues

Hospital Central do Exército

dayserodrigues@aluno.fiocruz.br+55-21-999761723

Outcome results

None listed

Source: REBEC (via WHO ICTRP)