Parkinson Disease
Conditions
Interventions
A single group of 18 patients with Parkinson's disease will be submitted to 3 experimental sessions (crossover study) performed in random order: moderate intensity aerobic exercise, high intensity aer
G11.427.590.530.698.277
Sponsors
Universidade Nove de Julho
Associação Brasil Parkinson
Eligibility
Age
50 Years to No maximum
Inclusion criteria
Inclusion criteria: previous diagnosis of Parkinson's Disease; being undergoing pharmacological treatment for Parkinson's Disease; be at least 50 years old
Exclusion criteria
Exclusion criteria: being in Hoehn & Yahr stages 4 or 5 of Parkinson's Disease; presenting other neurological diseases in addition to Parkinson's disease; present electrocardiographic alterations during exercise test suggestive of cardiovascular pathology; having a diagnosis of cardiovascular disease, cancer, or any type of dementia; score = 20 on the “Montreal Cognitive Assessment (MoCA)”; be performing aerobic training regularly; have musculoskeletal problems that interfere with performing aerobic exercise
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| It is expected to find a greater increase in executive function, verified by the Stroop Test of Colors and Words, after high-intensity aerobic exercise compared to moderate-intensity aerobic exercise, based on the verification of a statistically significant difference, defined as a P value < 0.05, in the post-exercise values ??between these interventions. ;It is expected to find a greater increase in executive function, verified by the Trail Making Test, after high-intensity aerobic exercise compared to moderate-intensity aerobic exercise, based on the verification of a statistically significant difference, defined as a P value < 0.05, in the post-exercise values ??between these interventions. | — |
Secondary
| Measure | Time frame |
|---|---|
| It is expected to find a greater increase in neurovascular coupling, assessed through transcranial Doppler, after high-intensity aerobic exercise compared to moderate-intensity aerobic exercise, based on the finding of a statistically significant difference, defined as a value of P < 0.05, in post-exercise values ??between these interventions. ;It is expected to find a greater increase in vasomotor reactivity, assessed through transcranial Doppler, after high-intensity aerobic exercise compared to moderate-intensity aerobic exercise, based on the finding of a statistically significant difference, defined as a value of P < 0.05, in post-exercise values ??between these interventions. ;It is expected to find a greater increase in cerebral blood flow, assessed by transcranial Doppler, during high-intensity aerobic exercise compared to moderate-intensity aerobic exercise, based on the finding of a statistically significant difference, defined as a P value < 0.05, in the values ??obtained during these interventions. | — |
Countries
Brazil
Contacts
Public ContactRaphael Ritti-Dias
Universidade Nove de Julho
Outcome results
None listed