Skip to content

Effect of Exercise before and after Arteriovenous Fistula creation in patients with Doença Renal Crônica in the conservative stage: randomised clinical trial

Effect of an Exercise Programm before and after Arteriovenous Fistula (AVF) creation for patients with Chronic Kidney Disease (CKD) in the conservative stage: randomised clinical trial

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
REBEC
Registry ID
RBR-103n2zss
Enrollment
Unknown
Registered
2024-04-24
Start date
2024-02-01
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Arteriovenous Fistula

Interventions

This is a randomised clinical trial which aims to evaluate the effects of na exercise programme for patients with Chronic Kidney Disease (CKD) with na indication for na arteriovenous fistula (AVF) cre
E02.760.169.063.500.387
I03.350

Sponsors

Hospital das Clínicas de Pernambuco
Lead Sponsor
Programa de Pós-Graduação em Fisioterapia da Universidade Federal de Pernambuco - UFPE
Collaborator

Eligibility

Age
35 Years to 70 Years

Inclusion criteria

Inclusion criteria: Men and women; aged between 35 and 70 years old; diagnosed with Chronic Kidney Disease (CKD) stage 4 and 5 with a Glomerular Filtration Rate (GFR) less than or equal to 20 ml/min/1.73 m2, followed up in an outpatient clinic by conservative treatment, who already have an indication to create a radiocephalic Arteriovenous Fistula (AVF) to perform haemodialysis, and patients who have had a distal Arteriovenous Fistula (AVF) fittel

Exclusion criteria

Exclusion criteria: Patients with a previous history of brachiocephalic Arteriovenous Fistula (AVF); those who exercise regularly; a history of vascular surgery in the upper limbs; the presence of vascular access in the upper limbs; occupational activities involving the handling of heavy loads; the presence of traumatic injuries, orthopaedic and rheumatological injuries in the cervical spine, shoulders, elbows, wrists and hands; signs of thrombophlebitis; hypoplasia or agenesis of the upper limbs; presence of cognitive impairment that makes it difficult to understand and finalize the assessment methodology and treatment protocol

Design outcomes

Primary

MeasureTime frame
It is expected to find an increase in the diameter (mm) of the cephalic vein assessed by doppler ultrasound before the study, after two weeks and after four weeks of applying the exercise protocol

Secondary

MeasureTime frame
We expected to find an increase in the distensibility (%) of the cephalic vein, an increase in the diameter (mm) of the radial artery, an increase in the blood flow rate (mL/min), an increase in the average velocity (cm/sec), and the peak blood flow (peak systolic) of the radial artery (cm/sec) assessed using Doppler ultrasound before the study, before and after the exercise protocol on the first and last day of treatment, after two weeks, and after four weeks of applying the exercise protocol. As well as an increase in forearm circumference (cm) measured with an anthropometric tape, an increase in handgrip strength (KgF) measured with an analogue dynamometer before, after two weeks, and after four weeks of applying the exercise protocol. Also expected is the perception of improvement and satisfaction with the proposed treatment as assessed by the Patient's Global Impression of Change Scale (PGICS) after four weeks of treatment

Countries

Brazil

Contacts

Public ContactJulio Policarpo

Universidade Federal de Pernambuco

julio.policarpo@ufpe.br+55-81-21268000

Outcome results

None listed

Source: REBEC (via WHO ICTRP) · Data processed: Feb 5, 2026