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RANDOMIZED STUDY OF PHASE II / III OF PACLITAXEL + CARBOPLATINO WITH OR WITHOUT BEVACIZUMAB IN PATIENTS WITH ADVANCED PULMON CANCER OR METASTASIC NO SCAMOSO NSCLC.

RANDOMIZED STUDY OF PHASE II / III OF PACLITAXEL + CARBOPLATINO WITH OR WITHOUT BEVACIZUMAB IN PATIENTS WITH ADVANCED PULMON CANCER OR METASTASIC NO SCAMOSO NSCLC.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
REPEC
Registry ID
PER-099-03
Enrollment
Unknown
Registered
2004-02-27
Start date
Unknown
Completion date
Unknown
Last updated
2023-09-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Paclitaxel / Carboplatin Type of group
Paclitaxel 200 mg / m2 infusion 3 hrs. day 1 / Carboplatin 6 AUC inf. 15-30 minutes on day 1, repeat each cycle every 3 weeks for 6 cycles. Group name:Paclitaxel / Carboplatin / Bevacizumab Type of group
Paclitaxel 200 mgr / m2 infusion 3 hrs. Day 1 / Carboplatin 6 AUC inf. 15-30 minutes on day 1 / Bevacizumab 15mgr./Kg. Inf. 90 minutes on day 1 after Carboplatin, repeat the cycles every 3 weeks for 6 cycles. After concluding the 6 courses will continue with Bevacizunimab only every 3 weeks until finding progression or toxicity not acceptable.

Sponsors

EASTERN COOPERATIVE ONCOLOGY GROUP (ECOG),
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: not contemplated

Exclusion criteria

Exclusion criteria: not contemplated

Design outcomes

Primary

MeasureTime frame
Outcome name:Lesions that can be accurately measured in at least one dimension (longest diameter to be recorded) as> 20 mm (2.0 cm) with conventional techniques or as> 10 mm (1.0 cm) with spiral CT sean. Measure:Toxicity and survival in patients with NM lung, not small cells with non-epidermolytic histology EC lll-B and EC IV treated with Carboplatin plus Paclitaxel +/- Bevadzumab. Timepoints:7 week

Secondary

MeasureTime frame
Outcome name:not contemplated Measure:not contemplated Timepoints:not contemplated

Countries

Peru

Outcome results

None listed

Source: REPEC (via WHO ICTRP)