FindTrial
Sign In

N-acetyl cysteine ​​and ACETAZOLAMIDE FOR THE TREATMENT OF CHRONIC MOUNTAIN SICKNESS IN SETTLERS OF HIGHLANDS OF THE PERUVIAN ANDES

N-acetyl cysteine ​​and ACETAZOLAMIDE FOR THE TREATMENT OF CHRONIC MOUNTAIN SICKNESS IN SETTLERS OF HIGHLANDS OF THE PERUVIAN ANDES

Status
Unknown
Phases
Unknown
Study type
Interventional
Source
REPEC
Registry ID
PER-050-12
Enrollment
112
Registered
2012-10-09
Start date
Unknown
Completion date
Unknown
Last updated
2023-09-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

A 6 WEEKS STUDY, IN MALE, AGE 18 WITH CHRONIC MOUNTAIN SICKNESS, WHO PREVIOUS INFORMED CONSENT SIGNATURE WILL BE RANDOMLY ASSIGNED TO FOUR GROUPS OF 28 VOLUNTEERS BY GROUP TO RECEIVE: 1. ACETAZOLAM

Sponsors

Thomas H Maren Foundation,
Lead Sponsor

Eligibility

Sex/Gender
Male
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: • MALE SUBJECT (WOMEN WILL BE EXCLUDED TO AVOID MENSTRUAL PROBLEMS) • AGE: 18 YEARS OR MORE. • HEMATOCRIT> 65%. • MMC SCORE> 6 (ANNEX 1). SCORE IS 0-3 IN THE PRESENCE OF 10 FEATURES INCLUDING: HEADACHE, DIZZINESS, MENTAL WEAKNESS, MENTAL FATIGUE, Dyspnea, INSOMNIA, TINNITUS, ANOREXIA, CYANOSIS, AND conjunctival hyperemia (1).

Exclusion criteria

Exclusion criteria: • PREVIOUS HISTORY OF ALLERGY / ADVERSE REACTION TO ACTZ OR NAC • SMOKING CIGARETTES OVER 5 / DAY. • PHLEBOTOMY IN THREE MONTHS PRIOR TO THE STUDY. • SERUM POTASSIUM 15 • PULMONARY DISEASE, ASTHMA INCLUDING, WITH THE REQUIREMENT OF USE OF OXYGEN. • Cirrhosis • ADRENAL FAILURE • Aspirin CONSUMPTION> 1 GR / DAY • CONTRAINDICATIONS FOR ARTERIAL BLOOD SAMPLING FROM RADIAL ARTERY.

Countries

Peru

Contacts

Public ContactAbdias Nicanor Hurtado

UNIVERSIDAD PERUANA CAYETANO HEREDIA

ahurtadoa@hotmail.com999858393

Outcome results

None listed

Source: REPEC (via WHO ICTRP)